Pharmaceutical Oral Formulation of Methionine as a Pediatric Treatment in Inherited Metabolic Disease

Pharmaceutical Oral Formulation of Methionine as a Pediatric Treatment in Inherited Metabolic Disease

L-Methionine (Met) is an essential alpha-amino acid playing a key role in several metabolic pathways. Rare inherited metabolic diseases such as mutations affecting the MARS1 gene encoding methionine tRNA synthetase (MetRS) can cause severe lung and liver disease before the age of two years. Oral Met...

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Bibliographic Details
Main Authors: Benjamin Querin, Arnaud Schweitzer-Chaput, Salvatore Cisternino, Sylvain Auvity, Anne-Sophie Fauqueur, Abdel Negbane, Alice Hadchouel, Joël Schlatter, Camille Cotteret
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceutics
Subjects:
acceptability
methionine
nutrient
rare disease
stability indicating
Online Access:https://www.mdpi.com/1999-4923/15/3/957

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