An Experimental Study Reveals the Protective Effect of Autophagy against Realgar-Induced Liver Injury via Suppressing ROS-Mediated NLRP3 Inflammasome Pathway

An Experimental Study Reveals the Protective Effect of Autophagy against Realgar-Induced Liver Injury via Suppressing ROS-Mediated NLRP3 Inflammasome Pathway

Realgar, a poisonous traditional Chinese medicine, has been shown to cause liver injury when used for long periods or overdoses. However, the underlying molecular mechanisms and therapeutic targets have not been fully elucidated. The aim of this study is to explore the role of autophagy in sub-chron...

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Bibliographic Details
Main Authors: Jing Yang, Jian Li, Haoqi Guo, Yuwei Zhang, Ziwei Guo, Yu Liu, Taoguang Huo
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
realgar
liver injury
autophagy
NLRP3 inflammasome
Online Access:https://www.mdpi.com/1422-0067/23/10/5697

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