HOX and PBX gene dysregulation as a therapeutic target in glioblastoma multiforme

HOX and PBX gene dysregulation as a therapeutic target in glioblastoma multiforme

Abstract Background Glioblastoma multiforme (GBM) is the most common high-grade malignant brain tumour in adults and arises from the glial cells in the brain. The prognosis of treated GBM remains very poor with 5-year survival rates of 5%, a figure which has not improved over the last few decades. C...

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Bibliographic Details
Main Authors: Einthavy Arunachalam, William Rogers, Guy R. Simpson, Carla Möller-Levet, Gemma Bolton, Mohammed Ismael, Christopher Smith, Karl Keegen, Izhar Bagwan, Tim Brend, Susan C. Short, Bangxing Hong, Yoshihiro Otani, Balveen Kaur, Nicola Annels, Richard Morgan, Hardev Pandha
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Cancer
Subjects:
Glioblastoma multiforme
HOX
PBX
Dysregulation
Online Access:https://doi.org/10.1186/s12885-022-09466-8

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