1,4:3,6-Dianhydrohexites
It is known that derivatives of isosorbide and isomannide can impart a sweet taste, for example, dimethyl ether of isosorbide is used as an ingredient in the production of chewing gums, hard sweets [1], isosorbide dipropanoate is widely used in the production of bakery products [1]. Mixed isohexite...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2024-01-01
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| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2024/01/bioconf_msnbas2024_01003.pdf |
| _version_ | 1797353076352352256 |
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| author | Bratash G.S. |
| author_facet | Bratash G.S. |
| author_sort | Bratash G.S. |
| collection | DOAJ |
| description | It is known that derivatives of isosorbide and isomannide can impart a sweet taste, for example, dimethyl ether of isosorbide is used as an ingredient in the production of chewing gums, hard sweets [1], isosorbide dipropanoate is widely used in the production of bakery products [1]. Mixed isohexite esters and esters (especially isosorbide) are used as flavor enhancers. Currently, isosorbide is proposed to be used as a component of the mixture used for the water-base ink pigment. This component has excellent dispersion stability, which is necessary for printing [1]. All production methods leading to isohexites use the corresponding hexitol as the starting material. To obtain isohexites with a quantitative yield, and in order to avoid adverse reactions, a number of techniques have been developed. The rate of the dehydration sequence in reactions using as the starting compound: 1,4-anhydro derivatives of D-iditol, D-gulitol, D-glucitol, and D-mannitol (from which 1,4:3,6-dianhydro compounds of isoidide (5) and isomannide (4) are obtained) depends on the location of the hydroxyl group (with5 endo as in D-mannitol and D-glucitol, or exo as in D-iditol and D-glucitol). All three isohexites (3-5) were studied by mass spectrometry, especially D-isomannide and their O-deuterated isomers, and 5-nitroisosorbide [1]. The isomannide cation formed as a result of dehydration reactions was also detected in the mass spectra of some isomannide derivatives [1]. Mass spectrometric analysis is used to determine isosorbide and its 5-nitro derivative in human urine and blood plasma. |
| first_indexed | 2024-03-08T13:25:59Z |
| format | Article |
| id | doaj.art-de1c0c8765b44569b57b101a8aa63113 |
| institution | Directory Open Access Journal |
| issn | 2117-4458 |
| language | English |
| last_indexed | 2024-03-08T13:25:59Z |
| publishDate | 2024-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj.art-de1c0c8765b44569b57b101a8aa631132024-01-17T14:58:25ZengEDP SciencesBIO Web of Conferences2117-44582024-01-01820100310.1051/bioconf/20248201003bioconf_msnbas2024_010031,4:3,6-DianhydrohexitesBratash G.S.0Russian State Agrarian University-Moscow Timiryazev Agricultural AcademyIt is known that derivatives of isosorbide and isomannide can impart a sweet taste, for example, dimethyl ether of isosorbide is used as an ingredient in the production of chewing gums, hard sweets [1], isosorbide dipropanoate is widely used in the production of bakery products [1]. Mixed isohexite esters and esters (especially isosorbide) are used as flavor enhancers. Currently, isosorbide is proposed to be used as a component of the mixture used for the water-base ink pigment. This component has excellent dispersion stability, which is necessary for printing [1]. All production methods leading to isohexites use the corresponding hexitol as the starting material. To obtain isohexites with a quantitative yield, and in order to avoid adverse reactions, a number of techniques have been developed. The rate of the dehydration sequence in reactions using as the starting compound: 1,4-anhydro derivatives of D-iditol, D-gulitol, D-glucitol, and D-mannitol (from which 1,4:3,6-dianhydro compounds of isoidide (5) and isomannide (4) are obtained) depends on the location of the hydroxyl group (with5 endo as in D-mannitol and D-glucitol, or exo as in D-iditol and D-glucitol). All three isohexites (3-5) were studied by mass spectrometry, especially D-isomannide and their O-deuterated isomers, and 5-nitroisosorbide [1]. The isomannide cation formed as a result of dehydration reactions was also detected in the mass spectra of some isomannide derivatives [1]. Mass spectrometric analysis is used to determine isosorbide and its 5-nitro derivative in human urine and blood plasma.https://www.bio-conferences.org/articles/bioconf/pdf/2024/01/bioconf_msnbas2024_01003.pdf |
| spellingShingle | Bratash G.S. 1,4:3,6-Dianhydrohexites BIO Web of Conferences |
| title | 1,4:3,6-Dianhydrohexites |
| title_full | 1,4:3,6-Dianhydrohexites |
| title_fullStr | 1,4:3,6-Dianhydrohexites |
| title_full_unstemmed | 1,4:3,6-Dianhydrohexites |
| title_short | 1,4:3,6-Dianhydrohexites |
| title_sort | 1 4 3 6 dianhydrohexites |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2024/01/bioconf_msnbas2024_01003.pdf |
| work_keys_str_mv | AT bratashgs 1436dianhydrohexites |