Evaluation of fibrinolytic medical therapy for patients with acute myocardial infarction
<p class="abstract"><strong> </strong><strong>BACKGROUND:</strong> Fibrinolytic therapy is the standard therapeutic method for patients with acute myocardial infarction (AMI). This study endeavored to assess the delay in arrival to the emer...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Vesnu Publications
2012-06-01
|
| Series: | ARYA Atherosclerosis |
| Online Access: | http://arya.mui.ac.ir/index.php/arya/article/view/353 |
| _version_ | 1818608196564025344 |
|---|---|
| author | Ali Maleki Arman Shariari Masoumeh Sadeghi Negin Rashidi Farshid Aliyari Saeid Forughi Behjat Nabatchi Reza Ganavati |
| author_facet | Ali Maleki Arman Shariari Masoumeh Sadeghi Negin Rashidi Farshid Aliyari Saeid Forughi Behjat Nabatchi Reza Ganavati |
| author_sort | Ali Maleki |
| collection | DOAJ |
| description | <p class="abstract"><strong> </strong><strong>BACKGROUND:</strong> Fibrinolytic therapy is the standard therapeutic method for patients with acute myocardial infarction (AMI). This study endeavored to assess the delay in arrival to the emergency department and door to needle time for thrombolytic therapy.</p> <p class="abstract"><strong> </strong><strong>METHODS:</strong> This study was conducted on 80 patients with AMI whom referred to our clinic from January 2009 to January 2010. We measured time of arrival, needle time and door to needle time for all patients. Moreover, the relations of these times to some variables such as age, gender and the referred shift of emergency department personnel were calculated.</p> <p class="abstract"><strong> RESULTS: </strong>A total of 80 patients, 62 (77.5%) male and 18 (22.5%) female were evaluated for thrombolytic therapy. The arrival time of overnight shifts was 14.59 ± 1.23 minutes shorter than other shifts. The median door to needle time was 46.56 minutes and the mean time of the onset of chest pain to arrival at the emergency department was 19.44 minutes. Seventy-two patients (90%) received fibrinolytic therapy within the first 30 minutes of arrival. The needle time was significantly longer in the night shift (P < 0.05) (between 8 to 14 minutes), while the time of receiving Streptokinase therapy in the other shifts was not meaningfully different. Finally there was a statistically significant difference between the referred shifts and needle time (P < 0.05).</p> <p class="abstract"><strong> </strong><strong>CONCLUSION:</strong> Despite our good results for door to needle time, to improve and attain the gold standard’s limits in administering fibrinolytic therapy, improvement of policies like training the personnel to shorten this time is recommend.</p> <p class="abstract"> </p><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td width="35" height="12"> </td></tr> <tr><td> </td> <td> </td></tr></tbody></table><p class="abstract"> </p> <strong>Keywords:</strong> Fibrinolytic Therapy, Door to Needle Time, Acute Myocardial Infarction |
| first_indexed | 2024-12-16T14:38:48Z |
| format | Article |
| id | doaj.art-de1d5c60dc4c4f12a20dcfcd42e93a31 |
| institution | Directory Open Access Journal |
| issn | 1735-3955 2251-6638 |
| language | English |
| last_indexed | 2024-12-16T14:38:48Z |
| publishDate | 2012-06-01 |
| publisher | Vesnu Publications |
| record_format | Article |
| series | ARYA Atherosclerosis |
| spelling | doaj.art-de1d5c60dc4c4f12a20dcfcd42e93a312022-12-21T22:28:02ZengVesnu PublicationsARYA Atherosclerosis1735-39552251-66382012-06-01814649310Evaluation of fibrinolytic medical therapy for patients with acute myocardial infarctionAli Maleki0Arman Shariari1Masoumeh Sadeghi2Negin Rashidi3Farshid Aliyari4Saeid Forughi5Behjat Nabatchi6Reza Ganavati7Assistant Professor, Department of Cardiology, Lorestan University of Medical Sciences, Khorramabad, Iran.General Practitioner, Lorestan University of Medical Sciences, Khorramabad, Iran.Associate Professor, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranInternist, Borujerd Hospitals, Borujerd University of Medical Sciences, Borujerd, Iran.Pathologist, Imam Khomeini Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran.MSc, School of Nursing, Lorestan University of Medical Sciences, Khorramabad, Iran.BSc, Nurse, Borujerd Hospitals, Borujerd University of Medical Sciences, Borujerd, IranCardiologist, Borujerd Hospitals, Borujerd University of Medical Sciences, Borujerd, Iran<p class="abstract"><strong> </strong><strong>BACKGROUND:</strong> Fibrinolytic therapy is the standard therapeutic method for patients with acute myocardial infarction (AMI). This study endeavored to assess the delay in arrival to the emergency department and door to needle time for thrombolytic therapy.</p> <p class="abstract"><strong> </strong><strong>METHODS:</strong> This study was conducted on 80 patients with AMI whom referred to our clinic from January 2009 to January 2010. We measured time of arrival, needle time and door to needle time for all patients. Moreover, the relations of these times to some variables such as age, gender and the referred shift of emergency department personnel were calculated.</p> <p class="abstract"><strong> RESULTS: </strong>A total of 80 patients, 62 (77.5%) male and 18 (22.5%) female were evaluated for thrombolytic therapy. The arrival time of overnight shifts was 14.59 ± 1.23 minutes shorter than other shifts. The median door to needle time was 46.56 minutes and the mean time of the onset of chest pain to arrival at the emergency department was 19.44 minutes. Seventy-two patients (90%) received fibrinolytic therapy within the first 30 minutes of arrival. The needle time was significantly longer in the night shift (P < 0.05) (between 8 to 14 minutes), while the time of receiving Streptokinase therapy in the other shifts was not meaningfully different. Finally there was a statistically significant difference between the referred shifts and needle time (P < 0.05).</p> <p class="abstract"><strong> </strong><strong>CONCLUSION:</strong> Despite our good results for door to needle time, to improve and attain the gold standard’s limits in administering fibrinolytic therapy, improvement of policies like training the personnel to shorten this time is recommend.</p> <p class="abstract"> </p><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td width="35" height="12"> </td></tr> <tr><td> </td> <td> </td></tr></tbody></table><p class="abstract"> </p> <strong>Keywords:</strong> Fibrinolytic Therapy, Door to Needle Time, Acute Myocardial Infarctionhttp://arya.mui.ac.ir/index.php/arya/article/view/353 |
| spellingShingle | Ali Maleki Arman Shariari Masoumeh Sadeghi Negin Rashidi Farshid Aliyari Saeid Forughi Behjat Nabatchi Reza Ganavati Evaluation of fibrinolytic medical therapy for patients with acute myocardial infarction ARYA Atherosclerosis |
| title | Evaluation of fibrinolytic medical therapy for patients with acute myocardial infarction |
| title_full | Evaluation of fibrinolytic medical therapy for patients with acute myocardial infarction |
| title_fullStr | Evaluation of fibrinolytic medical therapy for patients with acute myocardial infarction |
| title_full_unstemmed | Evaluation of fibrinolytic medical therapy for patients with acute myocardial infarction |
| title_short | Evaluation of fibrinolytic medical therapy for patients with acute myocardial infarction |
| title_sort | evaluation of fibrinolytic medical therapy for patients with acute myocardial infarction |
| url | http://arya.mui.ac.ir/index.php/arya/article/view/353 |
| work_keys_str_mv | AT alimaleki evaluationoffibrinolyticmedicaltherapyforpatientswithacutemyocardialinfarction AT armanshariari evaluationoffibrinolyticmedicaltherapyforpatientswithacutemyocardialinfarction AT masoumehsadeghi evaluationoffibrinolyticmedicaltherapyforpatientswithacutemyocardialinfarction AT neginrashidi evaluationoffibrinolyticmedicaltherapyforpatientswithacutemyocardialinfarction AT farshidaliyari evaluationoffibrinolyticmedicaltherapyforpatientswithacutemyocardialinfarction AT saeidforughi evaluationoffibrinolyticmedicaltherapyforpatientswithacutemyocardialinfarction AT behjatnabatchi evaluationoffibrinolyticmedicaltherapyforpatientswithacutemyocardialinfarction AT rezaganavati evaluationoffibrinolyticmedicaltherapyforpatientswithacutemyocardialinfarction |