Physiological ER stress caused by amylase production induces regulated Ire1-dependent mRNA decay in Aspergillus oryzae
Abstract Regulated Ire1-dependent decay (RIDD) is a feedback mechanism in which the endoribonuclease Ire1 cleaves endoplasmic reticulum (ER)-localized mRNAs encoding secretory and membrane proteins in eukaryotic cells under ER stress. RIDD is artificially induced by chemicals that generate ER stress...
Main Authors: | Mizuki Tanaka, Silai Zhang, Shun Sato, Jun-ichi Yokota, Yuko Sugiyama, Yasuaki Kawarasaki, Youhei Yamagata, Katsuya Gomi, Takahiro Shintani |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-05386-w |
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