Unveiling the role of miR-137-3p/miR-296-5p/SERPINA3 signaling in colorectal cancer progression: integrative analysis of gene expression profiles and in vitro studies

Unveiling the role of miR-137-3p/miR-296-5p/SERPINA3 signaling in colorectal cancer progression: integrative analysis of gene expression profiles and in vitro studies

Abstract Background Colorectal cancer (CRC) is a prevalent malignancy worldwide, with increasing incidence and mortality rates. Although treatment options have improved, CRC remains a leading cause of death due to metastasis. Early intervention can significantly improve patient outcomes, making it c...

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Bibliographic Details
Main Authors: Huimin Liu, Xingxing Wu, Dandan Wang, Quanxi Li, Xin Zhang, Liang Xu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Medical Genomics
Subjects:
Colorectal cancer
Metastasis
Bioinformatics analysis
DEGs
SERPINA3, miR-137-3p
miR-296-5p
Online Access:https://doi.org/10.1186/s12920-023-01763-w

Internet

https://doi.org/10.1186/s12920-023-01763-w

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