A Comparative Study on Fine Needle Aspiration Cytology versus Fine Needle Capillary Cytology in Thyroid Nodules
Objectives: Fine needle aspiration cytology (FNAC/FNA) is the primary investigation for thyroid nodules. Fine needle capillary cytology (FNCC/FNC) is an alternative technique not commonly used, though it is easy to perform. Both the techniques have their own advantages and disadvantages. This study...
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| Format: | Article |
| Language: | English |
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Oman Medical Specialty Board
2012-03-01
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| Series: | Oman Medical Journal |
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| Online Access: | http://journals.indexcopernicus.com/fulltxt.php?ICID=989908 |
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| author | Prathvi Shetty Divakar Shenoy P. Sathyamoorthy Aithala Celine George Hilda Fernandes Geover J. Lobo Leo F. Tauro |
| author_facet | Prathvi Shetty Divakar Shenoy P. Sathyamoorthy Aithala Celine George Hilda Fernandes Geover J. Lobo Leo F. Tauro |
| author_sort | Prathvi Shetty |
| collection | DOAJ |
| description | Objectives: Fine needle aspiration cytology (FNAC/FNA) is the primary investigation for thyroid nodules. Fine needle capillary cytology (FNCC/FNC) is an alternative technique not commonly used, though it is easy to perform. Both the techniques have their own advantages and disadvantages. This study aims to compare these two cytological techniques for better specimen and cytological diagnosis.Methods: This prospective study was conducted on 50 patients attending the FR Muller Medical College Hospital from May 2006 to April 2008. The patients with thyroid nodules (diagnosed by palpation) were subjected to both the cytological techniques; FNA and FNC. The specimen and results were compared and then correlated with the final histopathological findings wherever surgical specimens were available (38 cases).Results: The mean age of the patients was 39.16 with a female predominance. The majority of cases were diagnosed to have nodular goiters. The FNC technique yielded 88�0diagnostic superiority and adequate specimens compared to 94�0by FNA. Sensitivity was 50�0for FNC and 100�0for FNA while specificity was 100�0for both techniques; accuracy score was 97.4�0for FNC and 100�0for FNA in predicting malignancy. While sensitivity was 75�0for FNC and 100�0for FNA; specificity was 100�0for both techniques, and accuracy score was 97.4�0for FNC and 100�0for FNA in the prediction of neoplasia.Conclusion: The results indicated that there was no significant difference between the two techniques; if done in tandem can give better and accurate cytological diagnosis. In highly cellular lesions, in which abundant material was obtained, FNC was more likely to be diagnostically superior, but FNA can diagnose most of the lesions. In less cellular lesions, FNA is more likely to be diagnostically superior to FNC. |
| first_indexed | 2024-12-12T10:56:21Z |
| format | Article |
| id | doaj.art-de24836656964117a0b04a1c22cba081 |
| institution | Directory Open Access Journal |
| issn | 1999-768X 2070-5204 |
| language | English |
| last_indexed | 2024-12-12T10:56:21Z |
| publishDate | 2012-03-01 |
| publisher | Oman Medical Specialty Board |
| record_format | Article |
| series | Oman Medical Journal |
| spelling | doaj.art-de24836656964117a0b04a1c22cba0812022-12-22T00:26:38ZengOman Medical Specialty BoardOman Medical Journal1999-768X2070-52042012-03-01272151156A Comparative Study on Fine Needle Aspiration Cytology versus Fine Needle Capillary Cytology in Thyroid NodulesPrathvi ShettyDivakar ShenoyP. Sathyamoorthy AithalaCeline GeorgeHilda FernandesGeover J. LoboLeo F. TauroObjectives: Fine needle aspiration cytology (FNAC/FNA) is the primary investigation for thyroid nodules. Fine needle capillary cytology (FNCC/FNC) is an alternative technique not commonly used, though it is easy to perform. Both the techniques have their own advantages and disadvantages. This study aims to compare these two cytological techniques for better specimen and cytological diagnosis.Methods: This prospective study was conducted on 50 patients attending the FR Muller Medical College Hospital from May 2006 to April 2008. The patients with thyroid nodules (diagnosed by palpation) were subjected to both the cytological techniques; FNA and FNC. The specimen and results were compared and then correlated with the final histopathological findings wherever surgical specimens were available (38 cases).Results: The mean age of the patients was 39.16 with a female predominance. The majority of cases were diagnosed to have nodular goiters. The FNC technique yielded 88�0diagnostic superiority and adequate specimens compared to 94�0by FNA. Sensitivity was 50�0for FNC and 100�0for FNA while specificity was 100�0for both techniques; accuracy score was 97.4�0for FNC and 100�0for FNA in predicting malignancy. While sensitivity was 75�0for FNC and 100�0for FNA; specificity was 100�0for both techniques, and accuracy score was 97.4�0for FNC and 100�0for FNA in the prediction of neoplasia.Conclusion: The results indicated that there was no significant difference between the two techniques; if done in tandem can give better and accurate cytological diagnosis. In highly cellular lesions, in which abundant material was obtained, FNC was more likely to be diagnostically superior, but FNA can diagnose most of the lesions. In less cellular lesions, FNA is more likely to be diagnostically superior to FNC.http://journals.indexcopernicus.com/fulltxt.php?ICID=989908Cytologyfine needle biopsyneedle biopsyThyroid GlandNon- aspiration |
| spellingShingle | Prathvi Shetty Divakar Shenoy P. Sathyamoorthy Aithala Celine George Hilda Fernandes Geover J. Lobo Leo F. Tauro A Comparative Study on Fine Needle Aspiration Cytology versus Fine Needle Capillary Cytology in Thyroid Nodules Oman Medical Journal Cytology fine needle biopsy needle biopsy Thyroid Gland Non- aspiration |
| title | A Comparative Study on Fine Needle Aspiration Cytology versus Fine Needle Capillary Cytology in Thyroid Nodules |
| title_full | A Comparative Study on Fine Needle Aspiration Cytology versus Fine Needle Capillary Cytology in Thyroid Nodules |
| title_fullStr | A Comparative Study on Fine Needle Aspiration Cytology versus Fine Needle Capillary Cytology in Thyroid Nodules |
| title_full_unstemmed | A Comparative Study on Fine Needle Aspiration Cytology versus Fine Needle Capillary Cytology in Thyroid Nodules |
| title_short | A Comparative Study on Fine Needle Aspiration Cytology versus Fine Needle Capillary Cytology in Thyroid Nodules |
| title_sort | comparative study on fine needle aspiration cytology versus fine needle capillary cytology in thyroid nodules |
| topic | Cytology fine needle biopsy needle biopsy Thyroid Gland Non- aspiration |
| url | http://journals.indexcopernicus.com/fulltxt.php?ICID=989908 |
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