Vaccination of koalas with a recombinant Chlamydia pecorum major outer membrane protein induces antibodies of different specificity compared to those following a natural live infection.
Chlamydial infection in koalas is common across the east coast of Australia and causes significant morbidity, infertility and mortality. An effective vaccine to prevent the adverse consequences of chlamydial infections in koalas (particularly blindness and infertility in females) would provide an im...
Main Authors: | Avinash Kollipara, Adam Polkinghorne, Kenneth W Beagley, Peter Timms |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3783496?pdf=render |
Similar Items
-
Novel molecular markers of <it>Chlamydia pecorum </it>genetic diversity in the koala (<it>Phascolarctos cinereus</it>)
by: Timms Peter, et al.
Published: (2011-04-01) -
Preliminary characterisation of tumor necrosis factor alpha and interleukin-10 responses to Chlamydia pecorum infection in the koala (Phascolarctos cinereus).
by: Marina Mathew, et al.
Published: (2013-01-01) -
Antibody and Cytokine Responses of Koalas (Phascolarctos cinereus) Vaccinated with Recombinant Chlamydial Major Outer Membrane Protein (MOMP) with Two Different Adjuvants.
by: Shahneaz Ali Khan, et al.
Published: (2016-01-01) -
A Prototype Recombinant-Protein Based Chlamydia pecorum Vaccine Results in Reduced Chlamydial Burden and Less Clinical Disease in Free-Ranging Koalas (Phascolarctos cinereus).
by: Courtney Waugh, et al.
Published: (2016-01-01) -
Immunization of a wild koala population with a recombinant Chlamydia pecorum Major Outer Membrane Protein (MOMP) or Polymorphic Membrane Protein (PMP) based vaccine: New insights into immune response, protection and clearance.
by: Marion Desclozeaux, et al.
Published: (2017-01-01)