The Effect of Platelet-Rich Fibrin and Platelet-Rich Plasma in Secondary Alveolar Bone Grafting in Cleft Lip and Palate Patients: A Systematic Review
(1) <b>Background</b>: Cleft lip, alveolus, and palate are the most common congenital abnormalities in the world, occurring in one in seven hundred live births. Secondary alveolar bone grafting (SABG) is usually performed when the permanent canine root shows one-half to two-thirds of roo...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-03-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/13/7/1875 |
| _version_ | 1797212461294682112 |
|---|---|
| author | Showbanaa Thangarajah Rifqah Nordin Huann Lan Tan Hui Yuh Soh Syed Nabil |
| author_facet | Showbanaa Thangarajah Rifqah Nordin Huann Lan Tan Hui Yuh Soh Syed Nabil |
| author_sort | Showbanaa Thangarajah |
| collection | DOAJ |
| description | (1) <b>Background</b>: Cleft lip, alveolus, and palate are the most common congenital abnormalities in the world, occurring in one in seven hundred live births. Secondary alveolar bone grafting (SABG) is usually performed when the permanent canine root shows one-half to two-thirds of root development. To improve the surgical outcome, supplemental grafting materials such as platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) have been used as an adjunct. This review is designed to assess the efficacy of PRF and PRP in improving the outcome of SABG. (2) <b>Methods</b>: A comprehensive literature search was performed until 13 October 2022 on MEDLINE, EMBASE, The Cochrane Library, and Pubmed. The full text of potentially relevant studies was reviewed, and only randomised clinical trials (RCTs) were included based on the inclusion criteria. (3) <b>Results</b>: A total of 656 studies were screened, of which four were included for final review. All of the four included studies that evaluated the quantitative or qualitative surgical outcome in varied ways. (4) <b>Conclusions</b>: Results of this review suggest that both PRF or PRP and control group (without the use of PRF/PRP) achieved similar successful outcomes in bone height, bone density, and bone volume in both qualitative and quantitative assessment. |
| first_indexed | 2024-04-24T10:42:45Z |
| format | Article |
| id | doaj.art-de287e865c81452b90cd4145270a096d |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-04-24T10:42:45Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-de287e865c81452b90cd4145270a096d2024-04-12T13:20:54ZengMDPI AGJournal of Clinical Medicine2077-03832024-03-01137187510.3390/jcm13071875The Effect of Platelet-Rich Fibrin and Platelet-Rich Plasma in Secondary Alveolar Bone Grafting in Cleft Lip and Palate Patients: A Systematic ReviewShowbanaa Thangarajah0Rifqah Nordin1Huann Lan Tan2Hui Yuh Soh3Syed Nabil4Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, National University of Malaysia, Kuala Lumpur 50300, MalaysiaDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, National University of Malaysia, Kuala Lumpur 50300, MalaysiaDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, National University of Malaysia, Kuala Lumpur 50300, MalaysiaDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, National University of Malaysia, Kuala Lumpur 50300, MalaysiaDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, National University of Malaysia, Kuala Lumpur 50300, Malaysia(1) <b>Background</b>: Cleft lip, alveolus, and palate are the most common congenital abnormalities in the world, occurring in one in seven hundred live births. Secondary alveolar bone grafting (SABG) is usually performed when the permanent canine root shows one-half to two-thirds of root development. To improve the surgical outcome, supplemental grafting materials such as platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) have been used as an adjunct. This review is designed to assess the efficacy of PRF and PRP in improving the outcome of SABG. (2) <b>Methods</b>: A comprehensive literature search was performed until 13 October 2022 on MEDLINE, EMBASE, The Cochrane Library, and Pubmed. The full text of potentially relevant studies was reviewed, and only randomised clinical trials (RCTs) were included based on the inclusion criteria. (3) <b>Results</b>: A total of 656 studies were screened, of which four were included for final review. All of the four included studies that evaluated the quantitative or qualitative surgical outcome in varied ways. (4) <b>Conclusions</b>: Results of this review suggest that both PRF or PRP and control group (without the use of PRF/PRP) achieved similar successful outcomes in bone height, bone density, and bone volume in both qualitative and quantitative assessment.https://www.mdpi.com/2077-0383/13/7/1875platelet-rich fibrinplatelet-rich plasmasecondary alveolar bone gratingcleft lip and palatesystematic review |
| spellingShingle | Showbanaa Thangarajah Rifqah Nordin Huann Lan Tan Hui Yuh Soh Syed Nabil The Effect of Platelet-Rich Fibrin and Platelet-Rich Plasma in Secondary Alveolar Bone Grafting in Cleft Lip and Palate Patients: A Systematic Review Journal of Clinical Medicine platelet-rich fibrin platelet-rich plasma secondary alveolar bone grating cleft lip and palate systematic review |
| title | The Effect of Platelet-Rich Fibrin and Platelet-Rich Plasma in Secondary Alveolar Bone Grafting in Cleft Lip and Palate Patients: A Systematic Review |
| title_full | The Effect of Platelet-Rich Fibrin and Platelet-Rich Plasma in Secondary Alveolar Bone Grafting in Cleft Lip and Palate Patients: A Systematic Review |
| title_fullStr | The Effect of Platelet-Rich Fibrin and Platelet-Rich Plasma in Secondary Alveolar Bone Grafting in Cleft Lip and Palate Patients: A Systematic Review |
| title_full_unstemmed | The Effect of Platelet-Rich Fibrin and Platelet-Rich Plasma in Secondary Alveolar Bone Grafting in Cleft Lip and Palate Patients: A Systematic Review |
| title_short | The Effect of Platelet-Rich Fibrin and Platelet-Rich Plasma in Secondary Alveolar Bone Grafting in Cleft Lip and Palate Patients: A Systematic Review |
| title_sort | effect of platelet rich fibrin and platelet rich plasma in secondary alveolar bone grafting in cleft lip and palate patients a systematic review |
| topic | platelet-rich fibrin platelet-rich plasma secondary alveolar bone grating cleft lip and palate systematic review |
| url | https://www.mdpi.com/2077-0383/13/7/1875 |
| work_keys_str_mv | AT showbanaathangarajah theeffectofplateletrichfibrinandplateletrichplasmainsecondaryalveolarbonegraftingincleftlipandpalatepatientsasystematicreview AT rifqahnordin theeffectofplateletrichfibrinandplateletrichplasmainsecondaryalveolarbonegraftingincleftlipandpalatepatientsasystematicreview AT huannlantan theeffectofplateletrichfibrinandplateletrichplasmainsecondaryalveolarbonegraftingincleftlipandpalatepatientsasystematicreview AT huiyuhsoh theeffectofplateletrichfibrinandplateletrichplasmainsecondaryalveolarbonegraftingincleftlipandpalatepatientsasystematicreview AT syednabil theeffectofplateletrichfibrinandplateletrichplasmainsecondaryalveolarbonegraftingincleftlipandpalatepatientsasystematicreview AT showbanaathangarajah effectofplateletrichfibrinandplateletrichplasmainsecondaryalveolarbonegraftingincleftlipandpalatepatientsasystematicreview AT rifqahnordin effectofplateletrichfibrinandplateletrichplasmainsecondaryalveolarbonegraftingincleftlipandpalatepatientsasystematicreview AT huannlantan effectofplateletrichfibrinandplateletrichplasmainsecondaryalveolarbonegraftingincleftlipandpalatepatientsasystematicreview AT huiyuhsoh effectofplateletrichfibrinandplateletrichplasmainsecondaryalveolarbonegraftingincleftlipandpalatepatientsasystematicreview AT syednabil effectofplateletrichfibrinandplateletrichplasmainsecondaryalveolarbonegraftingincleftlipandpalatepatientsasystematicreview |