The C60-Fullerene Porphyrin Adducts for Prevention of the Doxorubicin-Induced Acute Cardiotoxicity in Rat Myocardial Cells

The C60-Fullerene Porphyrin Adducts for Prevention of the Doxorubicin-Induced Acute Cardiotoxicity in Rat Myocardial Cells

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"nThis is a fullerene-based low toxic nanocationite designed for targeted delivery of the paramagnetic stable isotope of magnesium to the doxorubicin (DXR)-induced damaged heart muscle providing a prominent effect close to about 80% recovery of the tissue hypoxia symptoms in less than 24 hr...

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Bibliographic Details
Main Authors: Seyed Vahid Shetab Boushehri, Seyed Nasser Ostad, Saeed Sarkar, Dmitry A. Kuznetsov, Anatoly L. Buchachenko, Marina A. Orlova, Bagher Minaii, Abbas Kebriaeezadeh, Seyed Mahdi Rezayat
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2010-09-01
Series:Acta Medica Iranica
Subjects:
Fullerene nanoparticles
doxorubicin-induced cardiotoxicity
25Mg2+
mitochondrial dysfunctions
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/16940.pdf&manuscript_id=16940

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