Epistasis for head morphology in <i>Drosophila melanogaster</i>
AbstractEpistasis—gene–gene interaction—is common for mutations with large phenotypic effects in humans and model organisms. Epistasis impacts quantitative genetic models of speciation, response to natural and artificial selection, genetic mapping, and personalized medicine. However, the existence a...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Oxford University Press
2021-08-01
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| Series: | G3: Genes, Genomes, Genetics |
| Online Access: | https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab285 |
| _version_ | 1818323498718724096 |
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| author | Ergi D Özsoy Murat Yılmaz Bahar Patlar Güzin Emecen Esra Durmaz Michael M Magwire Shanshan Zhou Wen Huang Robert R H Anholt Trudy F C Mackay |
| author_facet | Ergi D Özsoy Murat Yılmaz Bahar Patlar Güzin Emecen Esra Durmaz Michael M Magwire Shanshan Zhou Wen Huang Robert R H Anholt Trudy F C Mackay |
| author_sort | Ergi D Özsoy |
| collection | DOAJ |
| description | AbstractEpistasis—gene–gene interaction—is common for mutations with large phenotypic effects in humans and model organisms. Epistasis impacts quantitative genetic models of speciation, response to natural and artificial selection, genetic mapping, and personalized medicine. However, the existence and magnitude of epistasis between alleles with small quantitative phenotypic effects are controversial and difficult to assess. Here, we use the Drosophila melanogasterjing and inv |
| first_indexed | 2024-12-13T11:13:39Z |
| format | Article |
| id | doaj.art-de2b54106bb94ebeb647b7971a75e377 |
| institution | Directory Open Access Journal |
| issn | 2160-1836 |
| language | English |
| last_indexed | 2024-12-13T11:13:39Z |
| publishDate | 2021-08-01 |
| publisher | Oxford University Press |
| record_format | Article |
| series | G3: Genes, Genomes, Genetics |
| spelling | doaj.art-de2b54106bb94ebeb647b7971a75e3772022-12-21T23:48:41ZengOxford University PressG3: Genes, Genomes, Genetics2160-18362021-08-01111010.1093/g3journal/jkab285Epistasis for head morphology in <i>Drosophila melanogaster</i>Ergi D Özsoy0Murat Yılmaz1Bahar Patlar2https://orcid.org/0000-0002-0442-9061Güzin Emecen3Esra Durmaz4https://orcid.org/0000-0002-4345-2264Michael M Magwire5Shanshan Zhou6Wen Huang7https://orcid.org/0000-0001-6788-8364Robert R H Anholt8https://orcid.org/0000-0001-7196-8324Trudy F C Mackay9https://orcid.org/0000-0002-2312-7245Department of Biology, Functional and Evolutionary Genetics Laboratory (FEGL), Science Faculty, Hacettepe University, 06800 Beytepe, Ankara, TurkeyDepartment of Biology, Functional and Evolutionary Genetics Laboratory (FEGL), Science Faculty, Hacettepe University, 06800 Beytepe, Ankara, TurkeyDepartment of Biology, Functional and Evolutionary Genetics Laboratory (FEGL), Science Faculty, Hacettepe University, 06800 Beytepe, Ankara, TurkeyDepartment of Biology, Functional and Evolutionary Genetics Laboratory (FEGL), Science Faculty, Hacettepe University, 06800 Beytepe, Ankara, TurkeyDepartment of Biology, Functional and Evolutionary Genetics Laboratory (FEGL), Science Faculty, Hacettepe University, 06800 Beytepe, Ankara, TurkeyDepartment of Animal Science, Michigan State University, East Lansing, MI 48824, USADepartment of Animal Science, Michigan State University, East Lansing, MI 48824, USADepartment of Animal Science, Michigan State University, East Lansing, MI 48824, USADepartment of Genetics, North Carolina State University, Raleigh, NC 27695-7614, USADepartment of Genetics, North Carolina State University, Raleigh, NC 27695-7614, USAAbstractEpistasis—gene–gene interaction—is common for mutations with large phenotypic effects in humans and model organisms. Epistasis impacts quantitative genetic models of speciation, response to natural and artificial selection, genetic mapping, and personalized medicine. However, the existence and magnitude of epistasis between alleles with small quantitative phenotypic effects are controversial and difficult to assess. Here, we use the Drosophila melanogasterjing and invhttps://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab285 |
| spellingShingle | Ergi D Özsoy Murat Yılmaz Bahar Patlar Güzin Emecen Esra Durmaz Michael M Magwire Shanshan Zhou Wen Huang Robert R H Anholt Trudy F C Mackay Epistasis for head morphology in <i>Drosophila melanogaster</i> G3: Genes, Genomes, Genetics |
| title | Epistasis for head morphology in <i>Drosophila melanogaster</i> |
| title_full | Epistasis for head morphology in <i>Drosophila melanogaster</i> |
| title_fullStr | Epistasis for head morphology in <i>Drosophila melanogaster</i> |
| title_full_unstemmed | Epistasis for head morphology in <i>Drosophila melanogaster</i> |
| title_short | Epistasis for head morphology in <i>Drosophila melanogaster</i> |
| title_sort | epistasis for head morphology in i drosophila melanogaster i |
| url | https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab285 |
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