Recent Advances in Nanomedicine for the Diagnosis and Treatment of Prostate Cancer Bone Metastasis
Patients with advanced prostate cancer can develop painful and debilitating bone metastases. Currently available interventions for prostate cancer bone metastases, including chemotherapy, bisphosphonates, and radiopharmaceuticals, are only palliative. They can relieve pain, reduce complications (e.g...
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Format: | Article |
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MDPI AG
2021-01-01
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Series: | Molecules |
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Online Access: | https://www.mdpi.com/1420-3049/26/2/384 |
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author | Daniel E. Hagaman Jossana A. Damasco Joy Vanessa D. Perez Raniv D. Rojo Marites P. Melancon |
author_facet | Daniel E. Hagaman Jossana A. Damasco Joy Vanessa D. Perez Raniv D. Rojo Marites P. Melancon |
author_sort | Daniel E. Hagaman |
collection | DOAJ |
description | Patients with advanced prostate cancer can develop painful and debilitating bone metastases. Currently available interventions for prostate cancer bone metastases, including chemotherapy, bisphosphonates, and radiopharmaceuticals, are only palliative. They can relieve pain, reduce complications (e.g., bone fractures), and improve quality of life, but they do not significantly improve survival times. Therefore, additional strategies to enhance the diagnosis and treatment of prostate cancer bone metastases are needed. Nanotechnology is a versatile platform that has been used to increase the specificity and therapeutic efficacy of various treatments for prostate cancer bone metastases. In this review, we summarize preclinical research that utilizes nanotechnology to develop novel diagnostic imaging tools, translational models, and therapies to combat prostate cancer bone metastases. |
first_indexed | 2024-03-09T04:58:34Z |
format | Article |
id | doaj.art-de2bcfb97f424ab4ae5fcf0ed10bb31e |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-03-09T04:58:34Z |
publishDate | 2021-01-01 |
publisher | MDPI AG |
record_format | Article |
series | Molecules |
spelling | doaj.art-de2bcfb97f424ab4ae5fcf0ed10bb31e2023-12-03T13:03:35ZengMDPI AGMolecules1420-30492021-01-0126238410.3390/molecules26020384Recent Advances in Nanomedicine for the Diagnosis and Treatment of Prostate Cancer Bone MetastasisDaniel E. Hagaman0Jossana A. Damasco1Joy Vanessa D. Perez2Raniv D. Rojo3Marites P. Melancon4Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAPatients with advanced prostate cancer can develop painful and debilitating bone metastases. Currently available interventions for prostate cancer bone metastases, including chemotherapy, bisphosphonates, and radiopharmaceuticals, are only palliative. They can relieve pain, reduce complications (e.g., bone fractures), and improve quality of life, but they do not significantly improve survival times. Therefore, additional strategies to enhance the diagnosis and treatment of prostate cancer bone metastases are needed. Nanotechnology is a versatile platform that has been used to increase the specificity and therapeutic efficacy of various treatments for prostate cancer bone metastases. In this review, we summarize preclinical research that utilizes nanotechnology to develop novel diagnostic imaging tools, translational models, and therapies to combat prostate cancer bone metastases.https://www.mdpi.com/1420-3049/26/2/384prostate cancerbone metastasisnanotechnologynanomedicine |
spellingShingle | Daniel E. Hagaman Jossana A. Damasco Joy Vanessa D. Perez Raniv D. Rojo Marites P. Melancon Recent Advances in Nanomedicine for the Diagnosis and Treatment of Prostate Cancer Bone Metastasis Molecules prostate cancer bone metastasis nanotechnology nanomedicine |
title | Recent Advances in Nanomedicine for the Diagnosis and Treatment of Prostate Cancer Bone Metastasis |
title_full | Recent Advances in Nanomedicine for the Diagnosis and Treatment of Prostate Cancer Bone Metastasis |
title_fullStr | Recent Advances in Nanomedicine for the Diagnosis and Treatment of Prostate Cancer Bone Metastasis |
title_full_unstemmed | Recent Advances in Nanomedicine for the Diagnosis and Treatment of Prostate Cancer Bone Metastasis |
title_short | Recent Advances in Nanomedicine for the Diagnosis and Treatment of Prostate Cancer Bone Metastasis |
title_sort | recent advances in nanomedicine for the diagnosis and treatment of prostate cancer bone metastasis |
topic | prostate cancer bone metastasis nanotechnology nanomedicine |
url | https://www.mdpi.com/1420-3049/26/2/384 |
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