Ex-PRESS implantation for different types of glaucoma

AIM: To evaluate the clinical results, efficacy and safety of Ex-PRESS P200 glaucoma shunt implant in different types of medically uncontrolled glaucoma. METHODS: The study included 31 eyes of 31 patients that were unresponsive to medical antiglaucomatous therapy in whom Ex-PRESS P200 glaucoma shun...

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Main Authors: Meltem Guzin Altinel, Ayse Yagmur Kanra, Remzi Karadag, Huseyin Bayramlar
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2019-08-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2019/8/20190809.pdf
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author Meltem Guzin Altinel
Ayse Yagmur Kanra
Remzi Karadag
Huseyin Bayramlar
author_facet Meltem Guzin Altinel
Ayse Yagmur Kanra
Remzi Karadag
Huseyin Bayramlar
author_sort Meltem Guzin Altinel
collection DOAJ
description AIM: To evaluate the clinical results, efficacy and safety of Ex-PRESS P200 glaucoma shunt implant in different types of medically uncontrolled glaucoma. METHODS: The study included 31 eyes of 31 patients that were unresponsive to medical antiglaucomatous therapy in whom Ex-PRESS P200 glaucoma shunt implantation was performed. The demographic characteristics of the patients, type of glaucoma, complete ocular examination results, number of antiglaucomatous drugs before and after surgery, early and late complications of surgery, additional surgical and nonsurgical medical interventions, and success rates were investigated from the patients’ files, retrospectively. RESULTS: The mean postoperative follow-up time was 16.4±7.5mo. The preoperative mean corrected intraocular pressure (IOP) was 28.7±10.3 mm Hg and postoperative mean corrected IOP was 15.3±5.2 mm Hg (P<0.05) at the last visit. The mean IOP reduction was 39.9% when the preoperative and postoperative values of the last visits were compared. The average number of antiglaucomatous drug use decreased from 3.9±0.3 to 1.7±1.7 postoperatively (P<0.05). The use of antiglaucomatous medications at the last visit was more than in other studies in the literature. The most common complication was conjunctival leakage, which was seen in 7 patients. Other early complications were iris touch, intravitreal hemorrhage, hyphema, choroidal effusion, early transient hypotonia and corneal edema. One of the late complications was endophthalmitis which was seen in one case 6mo after the operation, and the other late complication was opacification of the cornea in one patient. Twelve additional surgical operations associated to Ex-PRESS surgery and 3 bleb needling have done. At the last visit, the complete success rate was 32.3% and the qualified success rate was 77.5% in all patients. CONCLUSION: Ex-PRESS P200 glaucoma shunt implantation may be an effective procedure for medically uncontrolled glaucoma with significantly lower use of antiglaucomatous medications.
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spelling doaj.art-de2c753e50bd472fa08ea31fcfa89a632022-12-22T01:01:18ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982019-08-011281290129710.18240/ijo.2019.08.09Ex-PRESS implantation for different types of glaucomaMeltem Guzin Altinel0Ayse Yagmur Kanra1Remzi Karadag2Huseyin Bayramlar3Department of Ophthalmology, Fatih Sultan Mehmet Training and Research Hospital, Icerenkoy Atasehir 34752, Istanbul, TurkeyDunyagoz Hospitals Group, Sultanbeyli 34337, Istanbul, TurkeyDepartment of Ophthalmology, Istanbul Medeniyet University School of Medicine, Goztepe Research and Training Hospital, Goztepe 34000, Istanbul, TurkeyDunyagoz Hospitals Group, Sultanbeyli 34337, Istanbul, TurkeyAIM: To evaluate the clinical results, efficacy and safety of Ex-PRESS P200 glaucoma shunt implant in different types of medically uncontrolled glaucoma. METHODS: The study included 31 eyes of 31 patients that were unresponsive to medical antiglaucomatous therapy in whom Ex-PRESS P200 glaucoma shunt implantation was performed. The demographic characteristics of the patients, type of glaucoma, complete ocular examination results, number of antiglaucomatous drugs before and after surgery, early and late complications of surgery, additional surgical and nonsurgical medical interventions, and success rates were investigated from the patients’ files, retrospectively. RESULTS: The mean postoperative follow-up time was 16.4±7.5mo. The preoperative mean corrected intraocular pressure (IOP) was 28.7±10.3 mm Hg and postoperative mean corrected IOP was 15.3±5.2 mm Hg (P<0.05) at the last visit. The mean IOP reduction was 39.9% when the preoperative and postoperative values of the last visits were compared. The average number of antiglaucomatous drug use decreased from 3.9±0.3 to 1.7±1.7 postoperatively (P<0.05). The use of antiglaucomatous medications at the last visit was more than in other studies in the literature. The most common complication was conjunctival leakage, which was seen in 7 patients. Other early complications were iris touch, intravitreal hemorrhage, hyphema, choroidal effusion, early transient hypotonia and corneal edema. One of the late complications was endophthalmitis which was seen in one case 6mo after the operation, and the other late complication was opacification of the cornea in one patient. Twelve additional surgical operations associated to Ex-PRESS surgery and 3 bleb needling have done. At the last visit, the complete success rate was 32.3% and the qualified success rate was 77.5% in all patients. CONCLUSION: Ex-PRESS P200 glaucoma shunt implantation may be an effective procedure for medically uncontrolled glaucoma with significantly lower use of antiglaucomatous medications.http://www.ijo.cn/en_publish/2019/8/20190809.pdfglaucomaex-press implantglaucoma surgery
spellingShingle Meltem Guzin Altinel
Ayse Yagmur Kanra
Remzi Karadag
Huseyin Bayramlar
Ex-PRESS implantation for different types of glaucoma
International Journal of Ophthalmology
glaucoma
ex-press implant
glaucoma surgery
title Ex-PRESS implantation for different types of glaucoma
title_full Ex-PRESS implantation for different types of glaucoma
title_fullStr Ex-PRESS implantation for different types of glaucoma
title_full_unstemmed Ex-PRESS implantation for different types of glaucoma
title_short Ex-PRESS implantation for different types of glaucoma
title_sort ex press implantation for different types of glaucoma
topic glaucoma
ex-press implant
glaucoma surgery
url http://www.ijo.cn/en_publish/2019/8/20190809.pdf
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AT ayseyagmurkanra expressimplantationfordifferenttypesofglaucoma
AT remzikaradag expressimplantationfordifferenttypesofglaucoma
AT huseyinbayramlar expressimplantationfordifferenttypesofglaucoma