Selection for female traits of high fertility affects male reproductive performance and alters the testicular transcriptional profile

Selection for female traits of high fertility affects male reproductive performance and alters the testicular transcriptional profile

Abstract Background Many genes important for reproductive performance are shared by both sexes. However, fecundity indices are primarily based on female parameters such as litter size. We examined a fertility mouse line (FL2), which has a considerably increased number of offspring and a total litter...

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Bibliographic Details
Main Authors: Marten Michaelis, Alexander Sobczak, Dirk Koczan, Martina Langhammer, Norbert Reinsch, Jennifer Schoen, Joachim M. Weitzel
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Genomics
Subjects:
Long-term selection mouse lines
Outbred mouse model
High-fertility
Fecundity
Testis
Reproductive fitness
Online Access:http://link.springer.com/article/10.1186/s12864-017-4288-z

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