Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer

Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer

Abstract Background Triple‐negative breast cancer (TNBC), a heterogeneous subtype of breast cancer (BC), had poor prognosis. Endoplasmic reticulum (ER) stress was responsible for cellular processes and played a crucial role in the cell function. ER stress is a complex and dynamic process that can in...

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Bibliographic Details
Main Authors: Xiaoqiang Zhang, Xuyu Chen, Fangze Qian, Yanhui Zhu, Gao He, Junzhe Yang, Xian Wu, Hongfei Zhang, Xiafei Yu, Xiaoan Liu
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Clinical and Translational Medicine
Subjects:
BAG6
Bcl‐2
endoplasmic reticulum stress
m6A
TNBC
USP19
Online Access:https://doi.org/10.1002/ctm2.1398

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