Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experience
Abstract Background Abdominal tuberculosis (TB) is an uncommon form of infection with Mycobacterium tuberculosis in Korea. In this study, we aimed to highlight the clinical features, diagnostic methods, and outcomes of abdominal TB over 12 years in Southeastern Korea. Methods A total of 139 patients...
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BMC
2018-12-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | http://link.springer.com/article/10.1186/s12879-018-3635-2 |
| _version_ | 1818283239032225792 |
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| author | Jin-Kyu Cho Young Min Choi Sang Soo Lee Hye Kyong Park Ra Ri Cha Wan Soo Kim Jin Joo Kim Jae Min Lee Hong Jun Kim Chang Yoon Ha Hyun Jin Kim Tae Hyo Kim Woon Tae Jung Ok Jae Lee |
| author_facet | Jin-Kyu Cho Young Min Choi Sang Soo Lee Hye Kyong Park Ra Ri Cha Wan Soo Kim Jin Joo Kim Jae Min Lee Hong Jun Kim Chang Yoon Ha Hyun Jin Kim Tae Hyo Kim Woon Tae Jung Ok Jae Lee |
| author_sort | Jin-Kyu Cho |
| collection | DOAJ |
| description | Abstract Background Abdominal tuberculosis (TB) is an uncommon form of infection with Mycobacterium tuberculosis in Korea. In this study, we aimed to highlight the clinical features, diagnostic methods, and outcomes of abdominal TB over 12 years in Southeastern Korea. Methods A total of 139 patients diagnosed as having abdominal TB who received anti-TB medication from January 2005 to June 2016 were reviewed. Among them, 69 patients (49.6%) had luminal TB, 28 (20.1%) had peritoneal TB, 7 (5.0%) had nodal TB, 23 (16.5%) had visceral TB, and 12 (8.6%) had mixed TB. Results The most frequent symptoms were abdominal pain (34.5%) and abdominal distension (21.0%). Diagnosis of abdominal TB was confirmed using microbiologic and/or histologic methods in 76 patients (confirmed diagnosis), while the remaining 63 patients were diagnosed based on clinical presentation and radiologic imaging (clinical diagnosis). According to diagnostic method, frequency of clinical diagnosis was highest in patients with luminal (50.7%) or peritoneal (64.3%) TB, while frequency of microscopic diagnosis was highest in patients with visceral TB (68.2%), and frequency of histologic diagnosis was highest in patients with nodal TB (85.2%). Interestingly, most patients, except those with nodal TB, showed a good response to anti-TB agents, with 84.2% showing a complete response. The mortality rate was only 1.4% in the present study. Conclusions Most patients responded very well to anti-TB therapy, and surgery was required in only a minority of cases of suspected abdominal TB. |
| first_indexed | 2024-12-13T00:33:44Z |
| format | Article |
| id | doaj.art-de32f6cca83f4fff95ff55d111b44e04 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-13T00:33:44Z |
| publishDate | 2018-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-de32f6cca83f4fff95ff55d111b44e042022-12-22T00:05:16ZengBMCBMC Infectious Diseases1471-23342018-12-011811810.1186/s12879-018-3635-2Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experienceJin-Kyu Cho0Young Min Choi1Sang Soo Lee2Hye Kyong Park3Ra Ri Cha4Wan Soo Kim5Jin Joo Kim6Jae Min Lee7Hong Jun Kim8Chang Yoon Ha9Hyun Jin Kim10Tae Hyo Kim11Woon Tae Jung12Ok Jae Lee13Department of Surgery, Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University Changwon HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalDepartment of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University HospitalAbstract Background Abdominal tuberculosis (TB) is an uncommon form of infection with Mycobacterium tuberculosis in Korea. In this study, we aimed to highlight the clinical features, diagnostic methods, and outcomes of abdominal TB over 12 years in Southeastern Korea. Methods A total of 139 patients diagnosed as having abdominal TB who received anti-TB medication from January 2005 to June 2016 were reviewed. Among them, 69 patients (49.6%) had luminal TB, 28 (20.1%) had peritoneal TB, 7 (5.0%) had nodal TB, 23 (16.5%) had visceral TB, and 12 (8.6%) had mixed TB. Results The most frequent symptoms were abdominal pain (34.5%) and abdominal distension (21.0%). Diagnosis of abdominal TB was confirmed using microbiologic and/or histologic methods in 76 patients (confirmed diagnosis), while the remaining 63 patients were diagnosed based on clinical presentation and radiologic imaging (clinical diagnosis). According to diagnostic method, frequency of clinical diagnosis was highest in patients with luminal (50.7%) or peritoneal (64.3%) TB, while frequency of microscopic diagnosis was highest in patients with visceral TB (68.2%), and frequency of histologic diagnosis was highest in patients with nodal TB (85.2%). Interestingly, most patients, except those with nodal TB, showed a good response to anti-TB agents, with 84.2% showing a complete response. The mortality rate was only 1.4% in the present study. Conclusions Most patients responded very well to anti-TB therapy, and surgery was required in only a minority of cases of suspected abdominal TB.http://link.springer.com/article/10.1186/s12879-018-3635-2TuberculosisAbdomenExtra-pulmonaryLuminalPeritoneal |
| spellingShingle | Jin-Kyu Cho Young Min Choi Sang Soo Lee Hye Kyong Park Ra Ri Cha Wan Soo Kim Jin Joo Kim Jae Min Lee Hong Jun Kim Chang Yoon Ha Hyun Jin Kim Tae Hyo Kim Woon Tae Jung Ok Jae Lee Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experience BMC Infectious Diseases Tuberculosis Abdomen Extra-pulmonary Luminal Peritoneal |
| title | Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experience |
| title_full | Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experience |
| title_fullStr | Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experience |
| title_full_unstemmed | Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experience |
| title_short | Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experience |
| title_sort | clinical features and outcomes of abdominal tuberculosis in southeastern korea 12 years of experience |
| topic | Tuberculosis Abdomen Extra-pulmonary Luminal Peritoneal |
| url | http://link.springer.com/article/10.1186/s12879-018-3635-2 |
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