SHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015
Introduction: The human-T cell lymphotropic virus is a retrovirus with various types known so far. HTLV-I and HTLV-II are of clinically importance as they cause different diseases such as adult T-cell leukemia/lymphoma, tropical spastic paraparesis, and human T-lymphotropic virus type I-associated m...
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| Format: | Article |
| Language: | English |
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Instituto Nacional de Salud
2018-03-01
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| Series: | Biomédica: revista del Instituto Nacional de Salud |
| Subjects: | |
| Online Access: | https://www.revistabiomedica.org/index.php/biomedica/article/view/3417 |
| _version_ | 1811220244618805248 |
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| author | Manuela Muñoz Santiago Carvalho Jorge Hernando Donado Gloria Eugenia Barco Sergio Jaramillo |
| author_facet | Manuela Muñoz Santiago Carvalho Jorge Hernando Donado Gloria Eugenia Barco Sergio Jaramillo |
| author_sort | Manuela Muñoz |
| collection | DOAJ |
| description | Introduction: The human-T cell lymphotropic virus is a retrovirus with various types known so far. HTLV-I and HTLV-II are of clinically importance as they cause different diseases such as adult T-cell leukemia/lymphoma, tropical spastic paraparesis, and human T-lymphotropic virus type I-associated myelopathy (HAM).
Objective: To estimate the prevalence of presumptive and confirmatory reactivity to HTLV-I/II in blood donors of Hospital Pablo Tobón Uribe Blood Bank between 2014 and 2015.
Materials and methods: The information was obtained from the Hospital Pablo Tobón Uribe Blood Bank database. We analyzed age, sex, place of origin, and place of residence of donors, and the reactivity using the screening test (ELISA) as well as the confirmatory test (immunoblot).
Results: The donor population studied included 6,275 men and 8,148 women, for a total of 14,423 donors recruited between March 1, 2014, and June 30, 2015. Of all tested donors, 25 were positive for HTLV-I/II by the screening test (ELISA). After performing the confirmatory test (immunoblot), only nine patients were positive for HTLV-I/II (36%), of whom eight were reactive to HTLV-I (32%) and one to HTLV-II (4%), for a global seroprevalence of 0.06% (CI 95%: 0.10-0.25).
Conclusions: Our findings were consistent with those found in similar studies in non-endemic areas of the country and with those from studies at international level reported in the literature. |
| first_indexed | 2024-04-12T07:39:28Z |
| format | Article |
| id | doaj.art-de342c4e76ba40e0adbb47183704ecbc |
| institution | Directory Open Access Journal |
| issn | 0120-4157 0120-4157 |
| language | English |
| last_indexed | 2024-04-12T07:39:28Z |
| publishDate | 2018-03-01 |
| publisher | Instituto Nacional de Salud |
| record_format | Article |
| series | Biomédica: revista del Instituto Nacional de Salud |
| spelling | doaj.art-de342c4e76ba40e0adbb47183704ecbc2022-12-22T03:41:52ZengInstituto Nacional de SaludBiomédica: revista del Instituto Nacional de Salud0120-41570120-41572018-03-01381374110.7705/biomedica.v38i0.34172041SHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015Manuela Muñoz0Santiago Carvalho1Jorge Hernando Donado2Gloria Eugenia Barco3Sergio Jaramillo4Facultad de Medicina, Universidad Pontificia Bolivariana, Medellín, ColombiaFacultad de Medicina, Universidad Pontificia Bolivariana, Medellín, ColombiaFacultad de Medicina, Universidad Pontificia Bolivariana, Medellín, Colombia Unidad de Investigaciones y Docencia, Hospital Pablo Tobón Uribe, Medellín, ColombiaBanco de Sangre, Hospital Pablo Tobón Uribe, Medellín, ColombiaDepartamento de Laboratorio Clínico y de Patología, Hospital Pablo Tobón Uribe, Medellín, ColombiaIntroduction: The human-T cell lymphotropic virus is a retrovirus with various types known so far. HTLV-I and HTLV-II are of clinically importance as they cause different diseases such as adult T-cell leukemia/lymphoma, tropical spastic paraparesis, and human T-lymphotropic virus type I-associated myelopathy (HAM). Objective: To estimate the prevalence of presumptive and confirmatory reactivity to HTLV-I/II in blood donors of Hospital Pablo Tobón Uribe Blood Bank between 2014 and 2015. Materials and methods: The information was obtained from the Hospital Pablo Tobón Uribe Blood Bank database. We analyzed age, sex, place of origin, and place of residence of donors, and the reactivity using the screening test (ELISA) as well as the confirmatory test (immunoblot). Results: The donor population studied included 6,275 men and 8,148 women, for a total of 14,423 donors recruited between March 1, 2014, and June 30, 2015. Of all tested donors, 25 were positive for HTLV-I/II by the screening test (ELISA). After performing the confirmatory test (immunoblot), only nine patients were positive for HTLV-I/II (36%), of whom eight were reactive to HTLV-I (32%) and one to HTLV-II (4%), for a global seroprevalence of 0.06% (CI 95%: 0.10-0.25). Conclusions: Our findings were consistent with those found in similar studies in non-endemic areas of the country and with those from studies at international level reported in the literature.https://www.revistabiomedica.org/index.php/biomedica/article/view/3417Human T-lymphotropic virus 1human T-lymphotropic virus 2blood donorsblood banksprevalenceRetroviridae |
| spellingShingle | Manuela Muñoz Santiago Carvalho Jorge Hernando Donado Gloria Eugenia Barco Sergio Jaramillo SHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015 Biomédica: revista del Instituto Nacional de Salud Human T-lymphotropic virus 1 human T-lymphotropic virus 2 blood donors blood banks prevalence Retroviridae |
| title | SHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015 |
| title_full | SHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015 |
| title_fullStr | SHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015 |
| title_full_unstemmed | SHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015 |
| title_short | SHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015 |
| title_sort | shtlv i ii seroprevalence in blood donors of hospital pablo tobon uribe blood bank during the period 2014 2015 |
| topic | Human T-lymphotropic virus 1 human T-lymphotropic virus 2 blood donors blood banks prevalence Retroviridae |
| url | https://www.revistabiomedica.org/index.php/biomedica/article/view/3417 |
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