Ketogenic essential amino acids modulate lipid synthetic pathways and prevent hepatic steatosis in mice.

Ketogenic essential amino acids modulate lipid synthetic pathways and prevent hepatic steatosis in mice.

Although dietary ketogenic essential amino acid (KAA) content modifies accumulation of hepatic lipids, the molecular interactions between KAAs and lipid metabolism are yet to be fully elucidated.We designed a diet with a high ratio (E/N) of essential amino acids (EAAs) to non-EAAs by partially repla...

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Bibliographic Details
Main Authors: Yasushi Noguchi, Natsumi Nishikata, Nahoko Shikata, Yoshiko Kimura, Jose O Aleman, Jamey D Young, Naoto Koyama, Joanne K Kelleher, Michio Takahashi, Gregory Stephanopoulos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2919399?pdf=render

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