Association between MICA polymorphisms, s-MICA levels, and pancreatic cancer risk in a population-based case-control study.

Association between MICA polymorphisms, s-MICA levels, and pancreatic cancer risk in a population-based case-control study.

<h4>Background</h4>Pancreatic tumor cells may avoid immune surveillance by releasing the transmembrane major histocompatibility complex class I chain-related A (MICA) protein in soluble form (s-MICA). We hypothesized that the presence of the A5.1 polymorphism in the MICA gene, which enco...

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Bibliographic Details
Main Authors: Guillaume Onyeaghala, John Lane, Nathan Pankratz, Heather H Nelson, Bharat Thyagarajan, Bruce Walcheck, Kristin E Anderson, Anna E Prizment
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217868

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