New and Old Genes Associated with Primary and Established Responses to Cisplatin and Topotecan Treatment in Ovarian Cancer Cell Lines

New and Old Genes Associated with Primary and Established Responses to Cisplatin and Topotecan Treatment in Ovarian Cancer Cell Lines

Low efficiency of chemotherapy in ovarian cancer results from the development of drug resistance. Cisplatin (CIS) and topotecan (TOP) are drugs used in chemotherapy of this cancer. We analyzed the development of CIS and TOP resistance in ovarian cancer cell lines. Incubation of drug sensitive cell l...

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Bibliographic Details
Main Authors: Monika Świerczewska, Andrzej Klejewski, Karolina Wojtowicz, Maciej Brązert, Dariusz Iżycki, Michał Nowicki, Maciej Zabel, Radosław Januchowski
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
ovarian cancer
cisplatin and topotecan resistance
new genes
Online Access:https://www.mdpi.com/1420-3049/22/10/1717

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