Subconfluent ARPE-19 Cells Display Mesenchymal Cell-State Characteristics and Behave like Fibroblasts, Rather Than Epithelial Cells, in Experimental HCMV Infection Studies

Subconfluent ARPE-19 Cells Display Mesenchymal Cell-State Characteristics and Behave like Fibroblasts, Rather Than Epithelial Cells, in Experimental HCMV Infection Studies

Human cytomegalovirus (HCMV) has a broad cellular tropism and epithelial cells are important physiological targets during infection. The retinal pigment epithelial cell line ARPE-19 has been used to model HCMV infection in epithelial cells for decades and remains a commonly used cell type for studyi...

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Bibliographic Details
Main Authors: Preethi Golconda, Mariana Andrade-Medina, Adam Oberstein
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Viruses
Subjects:
herpesvirus
cytomegalovirus
human cytomegalovirus
HCMV
EMT
ARPE-19
Online Access:https://www.mdpi.com/1999-4915/16/1/49

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