Physico-Chemical and Biological Properties of Biosimilar and Reference Tissue Plasminogen Activator Products

Physico-Chemical and Biological Properties of Biosimilar and Reference Tissue Plasminogen Activator Products

Recombinant tissue plasminogen activator (international nonproprietary name — alteplase) which was developed by «GENERIUM» (Russia) and received a marketing authorisation in Russia is completely analogous to Actilyse® which is used to treat medical conditions accompanied by thrombosis, such as acute...

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Bibliographic Details
Main Authors:	V. D. Gusarova, M. S. Pantyushenko, V. M. Simonov, R. R. Shukurov, R. A. Khamitov, A. Yu. Vishnevskiy
Format:	Article
Language:	Russian
Published:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2019-03-01
Series:	Биопрепараты: Профилактика, диагностика, лечение
Subjects:	tissue plasminogen activator biosimilar actilyse® revelyse® glycosylation profile post-translational modifications fibrin clot lysis
Online Access:	https://www.biopreparations.ru/jour/article/view/207

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