A novel mushroom (Auricularia polytricha) glycoprotein protects against lead-induced hepatoxicity, promotes lead adsorption, inhibits organ accumulation of lead, upregulates detoxifying proteins, and enhances immunoregulation in rats

A novel mushroom (Auricularia polytricha) glycoprotein protects against lead-induced hepatoxicity, promotes lead adsorption, inhibits organ accumulation of lead, upregulates detoxifying proteins, and enhances immunoregulation in rats

IntroductionLead is a ubiquitous environmental and industrial pollutant. Its nonbiodegradable toxicity induces a plethora of human diseases. A novel bioactive glycoprotein containing 1.15% carbohydrate, with the ability of adsorbing lead and effecting detoxification, has been purified from Auricular...

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Bibliographic Details
Main Authors: Shuang Zhao, Yi Gao, Hexiang Wang, Yangyang Fan, Pan Wang, Wenting Zhao, Jack Ho Wong, Dan Wang, Xiaoyan Zhao, Tzi Bun Ng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Nutrition
Subjects:
Auricularia polytricha
detoxification
glycoprotein
lead elimination activity
proteomics
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1144346/full

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https://www.frontiersin.org/articles/10.3389/fnut.2023.1144346/full

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