CELLULAR IMMUNITY OF THE PATIENTS SUFFERING FROM RECURRENT GENITAL CANDIDOSE
The examination of the cellular immunity parameters comprised 20 women suffering from the recurrent genital candidose (RGK) in the remission phase as well as 20 women of the control grooup that never had any verified genital mucous infection. The aim of the research was to determine the interferon-g...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University in Nis, Faculty of Medicine
2000-03-01
|
| Series: | Acta Medica Medianae |
| Subjects: | |
| Online Access: | http://publisher.medfak.ni.ac.rs/2000-html/2-broj/Celularni%20imunitet....pdf |
| _version_ | 1811324089819725824 |
|---|---|
| author | Nataša Miladinovic Predrag Vlahovic Gordana Tasic Suzana Tasic |
| author_facet | Nataša Miladinovic Predrag Vlahovic Gordana Tasic Suzana Tasic |
| author_sort | Nataša Miladinovic |
| collection | DOAJ |
| description | The examination of the cellular immunity parameters comprised 20 women suffering from the recurrent genital candidose (RGK) in the remission phase as well as 20 women of the control grooup that never had any verified genital mucous infection. The aim of the research was to determine the interferon-gamma (INF gamma) production in the culture of specifically (by the Candida albicans - HKB-antigens) and non-specifically (Concavalin-A-ConA) stimulated mononuclear cells of the peripheral blood of the women with the RKG as well as of the healthy women for the sake of determining a possible presence of the system cellular immunity hypo-activity. The IFN gamma was determined by the quantitative immuno-enzymic Quantikine method (R/D system, Minneapolis, USA).The IFN gamma was confirmed in minimal quantities in the cultures of the lymphocytes stimulated by the specific antigen (average value - 15 pg/ml). A considerably higher value of the produced IFN gamma was confirmed in the cultures of the stimulated lymphocytes (average value - 954 pg/ml) as well as at the ConA and the HKB lymphocyte stimulus (average value - 1247 pg/ml). |
| first_indexed | 2024-04-13T14:08:05Z |
| format | Article |
| id | doaj.art-de476f55945145ed9c5b6d96c40815d1 |
| institution | Directory Open Access Journal |
| issn | 0365-4478 |
| language | English |
| last_indexed | 2024-04-13T14:08:05Z |
| publishDate | 2000-03-01 |
| publisher | University in Nis, Faculty of Medicine |
| record_format | Article |
| series | Acta Medica Medianae |
| spelling | doaj.art-de476f55945145ed9c5b6d96c40815d12022-12-22T02:43:52ZengUniversity in Nis, Faculty of MedicineActa Medica Medianae0365-44782000-03-013921322CELLULAR IMMUNITY OF THE PATIENTS SUFFERING FROM RECURRENT GENITAL CANDIDOSENataša MiladinovicPredrag VlahovicGordana TasicSuzana TasicThe examination of the cellular immunity parameters comprised 20 women suffering from the recurrent genital candidose (RGK) in the remission phase as well as 20 women of the control grooup that never had any verified genital mucous infection. The aim of the research was to determine the interferon-gamma (INF gamma) production in the culture of specifically (by the Candida albicans - HKB-antigens) and non-specifically (Concavalin-A-ConA) stimulated mononuclear cells of the peripheral blood of the women with the RKG as well as of the healthy women for the sake of determining a possible presence of the system cellular immunity hypo-activity. The IFN gamma was determined by the quantitative immuno-enzymic Quantikine method (R/D system, Minneapolis, USA).The IFN gamma was confirmed in minimal quantities in the cultures of the lymphocytes stimulated by the specific antigen (average value - 15 pg/ml). A considerably higher value of the produced IFN gamma was confirmed in the cultures of the stimulated lymphocytes (average value - 954 pg/ml) as well as at the ConA and the HKB lymphocyte stimulus (average value - 1247 pg/ml).http://publisher.medfak.ni.ac.rs/2000-html/2-broj/Celularni%20imunitet....pdfRecurrent genital candidoseinterferon gamacellular immunity |
| spellingShingle | Nataša Miladinovic Predrag Vlahovic Gordana Tasic Suzana Tasic CELLULAR IMMUNITY OF THE PATIENTS SUFFERING FROM RECURRENT GENITAL CANDIDOSE Acta Medica Medianae Recurrent genital candidose interferon gama cellular immunity |
| title | CELLULAR IMMUNITY OF THE PATIENTS SUFFERING FROM RECURRENT GENITAL CANDIDOSE |
| title_full | CELLULAR IMMUNITY OF THE PATIENTS SUFFERING FROM RECURRENT GENITAL CANDIDOSE |
| title_fullStr | CELLULAR IMMUNITY OF THE PATIENTS SUFFERING FROM RECURRENT GENITAL CANDIDOSE |
| title_full_unstemmed | CELLULAR IMMUNITY OF THE PATIENTS SUFFERING FROM RECURRENT GENITAL CANDIDOSE |
| title_short | CELLULAR IMMUNITY OF THE PATIENTS SUFFERING FROM RECURRENT GENITAL CANDIDOSE |
| title_sort | cellular immunity of the patients suffering from recurrent genital candidose |
| topic | Recurrent genital candidose interferon gama cellular immunity |
| url | http://publisher.medfak.ni.ac.rs/2000-html/2-broj/Celularni%20imunitet....pdf |
| work_keys_str_mv | AT natasamiladinovic cellularimmunityofthepatientssufferingfromrecurrentgenitalcandidose AT predragvlahovic cellularimmunityofthepatientssufferingfromrecurrentgenitalcandidose AT gordanatasic cellularimmunityofthepatientssufferingfromrecurrentgenitalcandidose AT suzanatasic cellularimmunityofthepatientssufferingfromrecurrentgenitalcandidose |