Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing

Electrochemical aptamer-based sensors typically exhibit limited sensitivity especially when the area of electrode is reduced for miniaturization. Here, the authors demonstrate electrochemical transistors as universal on-site amplifiers for enhancement in sensitivity of over 3 orders of magnitude.

Bibliographic Details
Main Authors: Xudong Ji, Xuanyi Lin, Jonathan Rivnay
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37402-2
_version_ 1797859919025668096
author Xudong Ji
Xuanyi Lin
Jonathan Rivnay
author_facet Xudong Ji
Xuanyi Lin
Jonathan Rivnay
author_sort Xudong Ji
collection DOAJ
description Electrochemical aptamer-based sensors typically exhibit limited sensitivity especially when the area of electrode is reduced for miniaturization. Here, the authors demonstrate electrochemical transistors as universal on-site amplifiers for enhancement in sensitivity of over 3 orders of magnitude.
first_indexed 2024-04-09T21:37:20Z
format Article
id doaj.art-de4b23db7bfe4ef2a51c9d35cb62819b
institution Directory Open Access Journal
issn 2041-1723
language English
last_indexed 2024-04-09T21:37:20Z
publishDate 2023-03-01
publisher Nature Portfolio
record_format Article
series Nature Communications
spelling doaj.art-de4b23db7bfe4ef2a51c9d35cb62819b2023-03-26T11:13:32ZengNature PortfolioNature Communications2041-17232023-03-011411910.1038/s41467-023-37402-2Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensingXudong Ji0Xuanyi Lin1Jonathan Rivnay2Department of Biomedical Engineering, Northwestern UniversityCenter for Sleep and Circadian Biology, Northwestern UniversityDepartment of Biomedical Engineering, Northwestern UniversityElectrochemical aptamer-based sensors typically exhibit limited sensitivity especially when the area of electrode is reduced for miniaturization. Here, the authors demonstrate electrochemical transistors as universal on-site amplifiers for enhancement in sensitivity of over 3 orders of magnitude.https://doi.org/10.1038/s41467-023-37402-2
spellingShingle Xudong Ji
Xuanyi Lin
Jonathan Rivnay
Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing
Nature Communications
title Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing
title_full Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing
title_fullStr Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing
title_full_unstemmed Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing
title_short Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing
title_sort organic electrochemical transistors as on site signal amplifiers for electrochemical aptamer based sensing
url https://doi.org/10.1038/s41467-023-37402-2
work_keys_str_mv AT xudongji organicelectrochemicaltransistorsasonsitesignalamplifiersforelectrochemicalaptamerbasedsensing
AT xuanyilin organicelectrochemicaltransistorsasonsitesignalamplifiersforelectrochemicalaptamerbasedsensing
AT jonathanrivnay organicelectrochemicaltransistorsasonsitesignalamplifiersforelectrochemicalaptamerbasedsensing