Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing
Electrochemical aptamer-based sensors typically exhibit limited sensitivity especially when the area of electrode is reduced for miniaturization. Here, the authors demonstrate electrochemical transistors as universal on-site amplifiers for enhancement in sensitivity of over 3 orders of magnitude.
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-37402-2 |
_version_ | 1797859919025668096 |
---|---|
author | Xudong Ji Xuanyi Lin Jonathan Rivnay |
author_facet | Xudong Ji Xuanyi Lin Jonathan Rivnay |
author_sort | Xudong Ji |
collection | DOAJ |
description | Electrochemical aptamer-based sensors typically exhibit limited sensitivity especially when the area of electrode is reduced for miniaturization. Here, the authors demonstrate electrochemical transistors as universal on-site amplifiers for enhancement in sensitivity of over 3 orders of magnitude. |
first_indexed | 2024-04-09T21:37:20Z |
format | Article |
id | doaj.art-de4b23db7bfe4ef2a51c9d35cb62819b |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-09T21:37:20Z |
publishDate | 2023-03-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-de4b23db7bfe4ef2a51c9d35cb62819b2023-03-26T11:13:32ZengNature PortfolioNature Communications2041-17232023-03-011411910.1038/s41467-023-37402-2Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensingXudong Ji0Xuanyi Lin1Jonathan Rivnay2Department of Biomedical Engineering, Northwestern UniversityCenter for Sleep and Circadian Biology, Northwestern UniversityDepartment of Biomedical Engineering, Northwestern UniversityElectrochemical aptamer-based sensors typically exhibit limited sensitivity especially when the area of electrode is reduced for miniaturization. Here, the authors demonstrate electrochemical transistors as universal on-site amplifiers for enhancement in sensitivity of over 3 orders of magnitude.https://doi.org/10.1038/s41467-023-37402-2 |
spellingShingle | Xudong Ji Xuanyi Lin Jonathan Rivnay Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing Nature Communications |
title | Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing |
title_full | Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing |
title_fullStr | Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing |
title_full_unstemmed | Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing |
title_short | Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing |
title_sort | organic electrochemical transistors as on site signal amplifiers for electrochemical aptamer based sensing |
url | https://doi.org/10.1038/s41467-023-37402-2 |
work_keys_str_mv | AT xudongji organicelectrochemicaltransistorsasonsitesignalamplifiersforelectrochemicalaptamerbasedsensing AT xuanyilin organicelectrochemicaltransistorsasonsitesignalamplifiersforelectrochemicalaptamerbasedsensing AT jonathanrivnay organicelectrochemicaltransistorsasonsitesignalamplifiersforelectrochemicalaptamerbasedsensing |