Daxx plays a novel role in T cell survival but is dispensable in Fas-induced apoptosis.
Daxx was originally isolated as a Fas-binding protein. However, the in vivo function of Daxx in Fas-induced apoptosis has remained enigmatic. Fas plays an important role in homeostasis in the immune system. Fas gene mutations lead to autoimmune-lymphoproliferation (lpr) diseases characterized by hyp...
| Príomhchruthaitheoirí: | , , , , , |
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| Formáid: | Alt |
| Teanga: | English |
| Foilsithe / Cruthaithe: |
Public Library of Science (PLoS)
2017-01-01
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| Sraith: | PLoS ONE |
| Rochtain ar líne: | http://europepmc.org/articles/PMC5354431?pdf=render |