ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY
Vitamin D deficiency is one of the substantiated risk factors of osteoporosis. This vitamin is required to provide intestinal calcium absorption, bone metabolism regulation, and neuromuscular functions in the body. Vitamin D deficiency results in increased bone metabolism, causing bone loss progress...
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Format: | Article |
Language: | Russian |
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IMA-PRESS LLC
2009-06-01
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Series: | Современная ревматология |
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Online Access: | https://mrj.ima-press.net/mrj/article/view/231 |
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author | N V Toroptsova |
author_facet | N V Toroptsova |
author_sort | N V Toroptsova |
collection | DOAJ |
description | Vitamin D deficiency is one of the substantiated risk factors of osteoporosis. This vitamin is required to provide intestinal calcium absorption, bone metabolism regulation, and neuromuscular functions in the body. Vitamin D deficiency results in increased bone metabolism, causing bone loss progression and increasing the risk of fractures. Moreover, patients with vitamin D deficiency have a higher probability of fallings and loss of muscle mass, increasing in turn the risk of fractures. The combined formulation of alendronate and vitamin D as tablets is as effective as the mono-formulation of alendronate, but, furthermore, it has an additional advantage associated with the guaranteed vitamin D intake. At the same time the bioavailability of each component does not differ from the similar index when these agents are used alone. |
first_indexed | 2024-04-10T02:09:07Z |
format | Article |
id | doaj.art-de4f1b5fc76049ec9a1b0d3ccac7129b |
institution | Directory Open Access Journal |
issn | 1996-7012 2310-158X |
language | Russian |
last_indexed | 2024-04-10T02:09:07Z |
publishDate | 2009-06-01 |
publisher | IMA-PRESS LLC |
record_format | Article |
series | Современная ревматология |
spelling | doaj.art-de4f1b5fc76049ec9a1b0d3ccac7129b2023-03-13T08:39:20ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2009-06-0132788110.14412/1996-7012-2009-5461536ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPYN V ToroptsovaVitamin D deficiency is one of the substantiated risk factors of osteoporosis. This vitamin is required to provide intestinal calcium absorption, bone metabolism regulation, and neuromuscular functions in the body. Vitamin D deficiency results in increased bone metabolism, causing bone loss progression and increasing the risk of fractures. Moreover, patients with vitamin D deficiency have a higher probability of fallings and loss of muscle mass, increasing in turn the risk of fractures. The combined formulation of alendronate and vitamin D as tablets is as effective as the mono-formulation of alendronate, but, furthermore, it has an additional advantage associated with the guaranteed vitamin D intake. At the same time the bioavailability of each component does not differ from the similar index when these agents are used alone.https://mrj.ima-press.net/mrj/article/view/231остеопорозхолекальциферолалендронат |
spellingShingle | N V Toroptsova ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY Современная ревматология остеопороз холекальциферол алендронат |
title | ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY |
title_full | ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY |
title_fullStr | ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY |
title_full_unstemmed | ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY |
title_short | ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY |
title_sort | role of vitamin d in the efficiency of antiresorptive therapy |
topic | остеопороз холекальциферол алендронат |
url | https://mrj.ima-press.net/mrj/article/view/231 |
work_keys_str_mv | AT nvtoroptsova roleofvitamindintheefficiencyofantiresorptivetherapy |