Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
Current strategies for regulatory control of gene expression are orthogonal to the host organism mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory pathways in the parasite Plasmodium falciparum.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2016-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms10727 |
| _version_ | 1819194979649585152 |
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| author | Suresh M. Ganesan Alejandra Falla Stephen J. Goldfless Armiyaw S. Nasamu Jacquin C. Niles |
| author_facet | Suresh M. Ganesan Alejandra Falla Stephen J. Goldfless Armiyaw S. Nasamu Jacquin C. Niles |
| author_sort | Suresh M. Ganesan |
| collection | DOAJ |
| description | Current strategies for regulatory control of gene expression are orthogonal to the host organism mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory pathways in the parasite Plasmodium falciparum. |
| first_indexed | 2024-12-23T02:05:28Z |
| format | Article |
| id | doaj.art-de4f9192e8bb4c6ba4ebcaac687eed22 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-23T02:05:28Z |
| publishDate | 2016-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-de4f9192e8bb4c6ba4ebcaac687eed222022-12-21T18:03:54ZengNature PortfolioNature Communications2041-17232016-03-017111010.1038/ncomms10727Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasitesSuresh M. Ganesan0Alejandra Falla1Stephen J. Goldfless2Armiyaw S. Nasamu3Jacquin C. Niles4Department of Biological Engineering, Massachusetts Institute of TechnologyDepartment of Biological Engineering, Massachusetts Institute of TechnologyDepartment of Biological Engineering, Massachusetts Institute of TechnologyDepartment of Biological Engineering, Massachusetts Institute of TechnologyDepartment of Biological Engineering, Massachusetts Institute of TechnologyCurrent strategies for regulatory control of gene expression are orthogonal to the host organism mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory pathways in the parasite Plasmodium falciparum.https://doi.org/10.1038/ncomms10727 |
| spellingShingle | Suresh M. Ganesan Alejandra Falla Stephen J. Goldfless Armiyaw S. Nasamu Jacquin C. Niles Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites Nature Communications |
| title | Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
| title_full | Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
| title_fullStr | Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
| title_full_unstemmed | Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
| title_short | Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
| title_sort | synthetic rna protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
| url | https://doi.org/10.1038/ncomms10727 |
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