Adropin Stimulates Proliferation and Inhibits Adrenocortical Steroidogenesis in the Human Adrenal Carcinoma (HAC15) Cell Line

Adropin Stimulates Proliferation and Inhibits Adrenocortical Steroidogenesis in the Human Adrenal Carcinoma (HAC15) Cell Line

Adropin is a multifunctional peptide hormone encoded by the ENHO (energy homeostasis associated) gene. It plays a role in mechanisms related to increased adiposity, insulin resistance, as well as glucose, and lipid metabolism. The low adropin levels are strongly associated with obesity independent i...

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Bibliographic Details
Main Authors: Ewelina Stelcer, Paulina Milecka, Hanna Komarowska, Karol Jopek, Marianna Tyczewska, Marta Szyszka, Marta Lesniczak, Wiktoria Suchorska, Karlygash Bekova, Beata Szczepaniak, Marek Ruchala, Marek Karczewski, Tomasz Wierzbicki, Witold Szaflarski, Ludwik K. Malendowicz, Marcin Rucinski
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Endocrinology
Subjects:
adrenal
adropin
TGF-beta
HAC15
GPR19
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.561370/full

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