Dysfunction of von-Hippel Lindau factor causes reduced degradation of HIF leading to renal cancer. Hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen HIF destruction and could therefore increase renal cancer

Dysfunction of von-Hippel Lindau factor causes reduced degradation of HIF leading to renal cancer. Hypoxia-inducible factor-prolyl hydroxylase enzyme inhibitors also lessen HIF destruction and could therefore increase renal cancer

Bibliographic Details
Main Author: Helge Waldum
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Pharmacology
Subjects:
von Hippel Lindau factor
hypoxia inducible factor (HIF)
renal cancer
prolyl hydroxylase inhibitor (roxadustat)
renal anemia
erythropoietin producing cell
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1170796/full
Description
ISSN:1663-9812

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