Risk Factors of and Treatments for Pharyngocutaneous Fistula Occurring after Oropharynx and Hypopharynx Reconstruction
Background A pharyngocutaneous fistula is a common and difficult-to-manage complication after head and neck reconstruction. It can lead to serious complications such as flap failure, carotid artery rupture, and pharyngeal stricture, and may require additional surgery. Previous radiotherapy, a low s...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Medical Publishers, Inc.
2017-11-01
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| Series: | Archives of Plastic Surgery |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2017.00906 |
| _version_ | 1798041689401589760 |
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| author | Su Bin Do Chul Hoon Chung Yong Joon Chang Byeong Jun Kim Young Soo Rho |
| author_facet | Su Bin Do Chul Hoon Chung Yong Joon Chang Byeong Jun Kim Young Soo Rho |
| author_sort | Su Bin Do |
| collection | DOAJ |
| description | Background A pharyngocutaneous fistula is a common and difficult-to-manage complication after head and neck reconstruction. It can lead to serious complications such as flap failure, carotid artery rupture, and pharyngeal stricture, and may require additional surgery. Previous radiotherapy, a low serum albumin level, and a higher T stage have been proposed as contributing factors. We aimed to clarify the risk factors for pharyngocutaneous fistula in patients who underwent flap reconstruction and to describe our experiences in treating pharyngocutaneous fistula.
Methods Squamous cell carcinoma cases that underwent flap reconstruction after cancer resection from 1995 to 2013 were analyzed retrospectively. We investigated several significant clinical risk factors. The treatment modality was selected according to the size of the fistula and the state of the surrounding tissue, with options including conservative management, direct closure, flap surgery, and pharyngostoma formation.
Results A total of 127 cases (18 with fistulae) were analyzed. A higher T stage (P=0.048) and tube-type reconstruction (P=0.007) increased fistula incidence; other factors did not show statistical significance (P>0.05). Two cases were treated with conservative management, 1 case with direct closure, 4 cases with immediate reconstruction using a pectoralis major musculocutaneous flap, and 11 cases with direct closure (4 cases) or additional flap surgery (7 cases) after pharyngostoma formation.
Conclusions Pharyngocutaneous fistula requires global management from prevention to treatment. In cases of advanced-stage cancer and tube-type reconstruction, a more cautious approach should be employed. Once it occurs, an accurate diagnosis of the fistula and a thorough assessment of the surrounding tissue are necessary, and aggressive treatment should be implemented in order to ensure satisfactory long-term results. |
| first_indexed | 2024-04-11T22:25:04Z |
| format | Article |
| id | doaj.art-de53d999dbf649a9b7b2aef46b8b5f82 |
| institution | Directory Open Access Journal |
| issn | 2234-6163 2234-6171 |
| language | English |
| last_indexed | 2024-04-11T22:25:04Z |
| publishDate | 2017-11-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Archives of Plastic Surgery |
| spelling | doaj.art-de53d999dbf649a9b7b2aef46b8b5f822022-12-22T03:59:46ZengThieme Medical Publishers, Inc.Archives of Plastic Surgery2234-61632234-61712017-11-01440653053810.5999/aps.2017.00906861Risk Factors of and Treatments for Pharyngocutaneous Fistula Occurring after Oropharynx and Hypopharynx ReconstructionSu Bin Do0Chul Hoon Chung1Yong Joon Chang2Byeong Jun Kim3Young Soo Rho4Department of Plastic and Reconstructive Surgery, Hallym University College of Medicine, Seoul, KoreaDepartment of Plastic and Reconstructive Surgery, Hallym University College of Medicine, Seoul, KoreaDepartment of Plastic and Reconstructive Surgery, Hallym University College of Medicine, Seoul, KoreaDepartment of Plastic and Reconstructive Surgery, Hallym University College of Medicine, Seoul, KoreaDepartment of Otorhinolaryngology-Head and Neck Surgery, Hallym University College of Medicine, Seoul, KoreaBackground A pharyngocutaneous fistula is a common and difficult-to-manage complication after head and neck reconstruction. It can lead to serious complications such as flap failure, carotid artery rupture, and pharyngeal stricture, and may require additional surgery. Previous radiotherapy, a low serum albumin level, and a higher T stage have been proposed as contributing factors. We aimed to clarify the risk factors for pharyngocutaneous fistula in patients who underwent flap reconstruction and to describe our experiences in treating pharyngocutaneous fistula. Methods Squamous cell carcinoma cases that underwent flap reconstruction after cancer resection from 1995 to 2013 were analyzed retrospectively. We investigated several significant clinical risk factors. The treatment modality was selected according to the size of the fistula and the state of the surrounding tissue, with options including conservative management, direct closure, flap surgery, and pharyngostoma formation. Results A total of 127 cases (18 with fistulae) were analyzed. A higher T stage (P=0.048) and tube-type reconstruction (P=0.007) increased fistula incidence; other factors did not show statistical significance (P>0.05). Two cases were treated with conservative management, 1 case with direct closure, 4 cases with immediate reconstruction using a pectoralis major musculocutaneous flap, and 11 cases with direct closure (4 cases) or additional flap surgery (7 cases) after pharyngostoma formation. Conclusions Pharyngocutaneous fistula requires global management from prevention to treatment. In cases of advanced-stage cancer and tube-type reconstruction, a more cautious approach should be employed. Once it occurs, an accurate diagnosis of the fistula and a thorough assessment of the surrounding tissue are necessary, and aggressive treatment should be implemented in order to ensure satisfactory long-term results.http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2017.00906cutaneous fistulapostoperative complicationsmyocutaneous flapfree tissue flaps |
| spellingShingle | Su Bin Do Chul Hoon Chung Yong Joon Chang Byeong Jun Kim Young Soo Rho Risk Factors of and Treatments for Pharyngocutaneous Fistula Occurring after Oropharynx and Hypopharynx Reconstruction Archives of Plastic Surgery cutaneous fistula postoperative complications myocutaneous flap free tissue flaps |
| title | Risk Factors of and Treatments for Pharyngocutaneous Fistula Occurring after Oropharynx and Hypopharynx Reconstruction |
| title_full | Risk Factors of and Treatments for Pharyngocutaneous Fistula Occurring after Oropharynx and Hypopharynx Reconstruction |
| title_fullStr | Risk Factors of and Treatments for Pharyngocutaneous Fistula Occurring after Oropharynx and Hypopharynx Reconstruction |
| title_full_unstemmed | Risk Factors of and Treatments for Pharyngocutaneous Fistula Occurring after Oropharynx and Hypopharynx Reconstruction |
| title_short | Risk Factors of and Treatments for Pharyngocutaneous Fistula Occurring after Oropharynx and Hypopharynx Reconstruction |
| title_sort | risk factors of and treatments for pharyngocutaneous fistula occurring after oropharynx and hypopharynx reconstruction |
| topic | cutaneous fistula postoperative complications myocutaneous flap free tissue flaps |
| url | http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2017.00906 |
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