Imbalance of glutamatergic and GABAergic neurotransmission in audiogenic seizure-susceptible Leucine-rich glioma-inactivated 1 (Lgi1)-mutant rats
Leucine-rich glioma-inactivated 1 (LGI1) was identified as a causative gene of autosomal dominant lateral temporal lobe epilepsy. We previously reported that Lgi1-mutant rats carrying a missense mutation (L385R) showed audiogenic seizure-susceptibility. To explore the pathophysiological mechanisms u...
Автори: | , , , , , , , , |
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Формат: | Стаття |
Мова: | English |
Опубліковано: |
Elsevier
2023-07-01
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Серія: | Heliyon |
Предмети: | |
Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S2405844023051927 |