Impact of lifestyle modification on glycemic control and cognitive function among Type II diabetes mellitus patients
Aim: Assessing impact of lifestyle modification on Type 2 diabetes mellitus (T2DM) glycemic control and cognitive function. Subjects & methods: Prospective study was conducted on T2DM patients (92 patients as interventional group and 92 patients conventional therapy). Results: After 6 months, si...
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| Format: | Article |
| Language: | English |
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Future Science Ltd
2023-01-01
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| Series: | Future Science OA |
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| Online Access: | https://www.future-science.com/doi/10.2144/fsoa-2022-0060 |
| _version_ | 1797861382234832896 |
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| author | Iman I Salama Samia M Sami Somaia I Salama Ghada A Abdel-Latif Ahmed Aboulghate Hala M Raslan Amira Mohsen Hanaa Rasmy Mona Hamed Ibrahim Mona MF Ganem Aida M Abdelmohsen Lobna A El-Etreby Nihad A Ibrahim Walaa A Fouad Sherif E El-Deeb |
| author_facet | Iman I Salama Samia M Sami Somaia I Salama Ghada A Abdel-Latif Ahmed Aboulghate Hala M Raslan Amira Mohsen Hanaa Rasmy Mona Hamed Ibrahim Mona MF Ganem Aida M Abdelmohsen Lobna A El-Etreby Nihad A Ibrahim Walaa A Fouad Sherif E El-Deeb |
| author_sort | Iman I Salama |
| collection | DOAJ |
| description | Aim: Assessing impact of lifestyle modification on Type 2 diabetes mellitus (T2DM) glycemic control and cognitive function. Subjects & methods: Prospective study was conducted on T2DM patients (92 patients as interventional group and 92 patients conventional therapy). Results: After 6 months, significant improvements of HbA1c, oxidant and antioxidant, lipid profile, and cognitive function among only the interventional group (p < 0.05). Using logistic analysis, conventional therapy, DM duration >10 years, lower education, HbA1c baseline >7 were significant predictive risks for uncontrolled DM (AOR 4.2, 2.9, 2.7 and 2.2, respectively). While, conventional therapy, baseline mild cognitive impairment (MCI) and females were significant risks for MCI (AOR 11.5, 10.8 and 4.8, respectively). Conclusion: Lifestyle modification is a very important for glycemic control and cognitive function. Clinical Trial Registration: NCT04891887 (ClinicalTrials.gov) |
| first_indexed | 2024-04-09T22:02:38Z |
| format | Article |
| id | doaj.art-de5ae33ef7e74dceb6f4bbe5eb3394bc |
| institution | Directory Open Access Journal |
| issn | 2056-5623 |
| language | English |
| last_indexed | 2024-04-09T22:02:38Z |
| publishDate | 2023-01-01 |
| publisher | Future Science Ltd |
| record_format | Article |
| series | Future Science OA |
| spelling | doaj.art-de5ae33ef7e74dceb6f4bbe5eb3394bc2023-03-23T16:30:49ZengFuture Science LtdFuture Science OA2056-56232023-01-019110.2144/fsoa-2022-0060Impact of lifestyle modification on glycemic control and cognitive function among Type II diabetes mellitus patientsIman I Salama0Samia M Sami1Somaia I Salama2Ghada A Abdel-Latif3Ahmed Aboulghate4Hala M Raslan5Amira Mohsen6Hanaa Rasmy7Mona Hamed Ibrahim8Mona MF Ganem9Aida M Abdelmohsen10Lobna A El-Etreby11Nihad A Ibrahim12Walaa A Fouad13Sherif E El-Deeb141Community Medicine Research Department, National Research Center, Cairo, 12622, Egypt2Child Health Department, National Research Center, Cairo, 12622, Egypt1Community Medicine Research Department, National Research Center, Cairo, 12622, Egypt1Community Medicine Research Department, National Research Center, Cairo, 12622, Egypt1Community Medicine Research Department, National Research Center, Cairo, 12622, Egypt3Internal Medicine Department, National Research Center, Cairo, 12622, Egypt1Community Medicine Research Department, National Research Center, Cairo, 12622, Egypt4Clinical & Chemical Pathology Department, Centre of Excellence, National Research Centre, Cairo, 12622, Egypt4Clinical & Chemical Pathology Department, Centre of Excellence, National Research Centre, Cairo, 12622, Egypt3Internal Medicine Department, National Research Center, Cairo, 12622, Egypt1Community Medicine Research Department, National Research Center, Cairo, 12622, Egypt1Community Medicine Research Department, National Research Center, Cairo, 12622, Egypt1Community Medicine Research Department, National Research Center, Cairo, 12622, Egypt1Community Medicine Research Department, National Research Center, Cairo, 12622, Egypt1Community Medicine Research Department, National Research Center, Cairo, 12622, EgyptAim: Assessing impact of lifestyle modification on Type 2 diabetes mellitus (T2DM) glycemic control and cognitive function. Subjects & methods: Prospective study was conducted on T2DM patients (92 patients as interventional group and 92 patients conventional therapy). Results: After 6 months, significant improvements of HbA1c, oxidant and antioxidant, lipid profile, and cognitive function among only the interventional group (p < 0.05). Using logistic analysis, conventional therapy, DM duration >10 years, lower education, HbA1c baseline >7 were significant predictive risks for uncontrolled DM (AOR 4.2, 2.9, 2.7 and 2.2, respectively). While, conventional therapy, baseline mild cognitive impairment (MCI) and females were significant risks for MCI (AOR 11.5, 10.8 and 4.8, respectively). Conclusion: Lifestyle modification is a very important for glycemic control and cognitive function. Clinical Trial Registration: NCT04891887 (ClinicalTrials.gov)https://www.future-science.com/doi/10.2144/fsoa-2022-0060cognitive functionglycemic controllifestyle modificationT2DM |
| spellingShingle | Iman I Salama Samia M Sami Somaia I Salama Ghada A Abdel-Latif Ahmed Aboulghate Hala M Raslan Amira Mohsen Hanaa Rasmy Mona Hamed Ibrahim Mona MF Ganem Aida M Abdelmohsen Lobna A El-Etreby Nihad A Ibrahim Walaa A Fouad Sherif E El-Deeb Impact of lifestyle modification on glycemic control and cognitive function among Type II diabetes mellitus patients Future Science OA cognitive function glycemic control lifestyle modification T2DM |
| title | Impact of lifestyle modification on glycemic control and cognitive function among Type II diabetes mellitus patients |
| title_full | Impact of lifestyle modification on glycemic control and cognitive function among Type II diabetes mellitus patients |
| title_fullStr | Impact of lifestyle modification on glycemic control and cognitive function among Type II diabetes mellitus patients |
| title_full_unstemmed | Impact of lifestyle modification on glycemic control and cognitive function among Type II diabetes mellitus patients |
| title_short | Impact of lifestyle modification on glycemic control and cognitive function among Type II diabetes mellitus patients |
| title_sort | impact of lifestyle modification on glycemic control and cognitive function among type ii diabetes mellitus patients |
| topic | cognitive function glycemic control lifestyle modification T2DM |
| url | https://www.future-science.com/doi/10.2144/fsoa-2022-0060 |
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