Clinical Features of Rotavirus Gastroenteritis and Their Association With Different Electropherotypes

From June 1993 to June 1995 stool samples were obtained from 377 children with acute diarrhea admitted to the Antonio Patricio de Alcalá Hospital in Cumaná, Venezuela. Electrophoretic patterns of rotaviruses were detected in 27.85 per cent (105/377) of fecal samples. The long pattern (80%) prevailed...

Full description

Bibliographic Details
Main Authors: María Z Sulbarán, Antonio J Maldonado, Yacqueline Rojas, Jesús W Bastardo
Format: Article
Language:English
Published: Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales 2002-11-01
Series:Kasmera
Subjects:
Online Access:https://produccioncientificaluz.org/index.php/kasmera/article/view/4700
_version_ 1797721887061573632
author María Z Sulbarán
Antonio J Maldonado
Yacqueline Rojas
Jesús W Bastardo
author_facet María Z Sulbarán
Antonio J Maldonado
Yacqueline Rojas
Jesús W Bastardo
author_sort María Z Sulbarán
collection DOAJ
description From June 1993 to June 1995 stool samples were obtained from 377 children with acute diarrhea admitted to the Antonio Patricio de Alcalá Hospital in Cumaná, Venezuela. Electrophoretic patterns of rotaviruses were detected in 27.85 per cent (105/377) of fecal samples. The long pattern (80%) prevailed over the short pattern (18.09%) and 2 specimens (1.91%) exhibited mixtures of electropherotypes. Viral RNA coelectrophoresis showed 6 distinct patterns, 4 electropherotypes of long profiles and 2 of short profiles. Association was found among the distinct electropherotypes detected and the clinical features of the illness. It was observed that the duration of diarrhea ranged from 3 to 6 days (73.8%), minimum daily evacuation was 1 to 2 times (85.4%), maximum daily evacuation was 5 to 8 times (58,1%). Most of the children showed a moderate dehydration (79,0?%), did not have fever (78,1%), and the duration of vomiting ranged from 1 to 4 days (74.2%). These results suggest that all electropherotypes behaved in a similar way and therefore did not provide information to establish the severity of the infection. Consequently it seems unlikely that the electropherotypes can be used to identify more virulent strains of rotavirus.
first_indexed 2024-03-12T09:39:35Z
format Article
id doaj.art-de5e06c889c34098af3e498890891cd4
institution Directory Open Access Journal
issn 0075-5222
2477-9628
language English
last_indexed 2024-03-12T09:39:35Z
publishDate 2002-11-01
publisher Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales
record_format Article
series Kasmera
spelling doaj.art-de5e06c889c34098af3e498890891cd42023-09-02T13:21:46ZengUniversidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y TropicalesKasmera0075-52222477-96282002-11-0130212613624278Clinical Features of Rotavirus Gastroenteritis and Their Association With Different ElectropherotypesMaría Z Sulbarán0Antonio J Maldonado1Yacqueline Rojas2Jesús W Bastardo3Universidad del OrienteUniversidad del OrienteUniversidad del OrienteUniversidad del OrienteFrom June 1993 to June 1995 stool samples were obtained from 377 children with acute diarrhea admitted to the Antonio Patricio de Alcalá Hospital in Cumaná, Venezuela. Electrophoretic patterns of rotaviruses were detected in 27.85 per cent (105/377) of fecal samples. The long pattern (80%) prevailed over the short pattern (18.09%) and 2 specimens (1.91%) exhibited mixtures of electropherotypes. Viral RNA coelectrophoresis showed 6 distinct patterns, 4 electropherotypes of long profiles and 2 of short profiles. Association was found among the distinct electropherotypes detected and the clinical features of the illness. It was observed that the duration of diarrhea ranged from 3 to 6 days (73.8%), minimum daily evacuation was 1 to 2 times (85.4%), maximum daily evacuation was 5 to 8 times (58,1%). Most of the children showed a moderate dehydration (79,0?%), did not have fever (78,1%), and the duration of vomiting ranged from 1 to 4 days (74.2%). These results suggest that all electropherotypes behaved in a similar way and therefore did not provide information to establish the severity of the infection. Consequently it seems unlikely that the electropherotypes can be used to identify more virulent strains of rotavirus.https://produccioncientificaluz.org/index.php/kasmera/article/view/4700Rotavirus, electroforesis, electroferotipos, características clínicas, diarrea, niños
spellingShingle María Z Sulbarán
Antonio J Maldonado
Yacqueline Rojas
Jesús W Bastardo
Clinical Features of Rotavirus Gastroenteritis and Their Association With Different Electropherotypes
Kasmera
Rotavirus, electroforesis, electroferotipos, características clínicas, diarrea, niños
title Clinical Features of Rotavirus Gastroenteritis and Their Association With Different Electropherotypes
title_full Clinical Features of Rotavirus Gastroenteritis and Their Association With Different Electropherotypes
title_fullStr Clinical Features of Rotavirus Gastroenteritis and Their Association With Different Electropherotypes
title_full_unstemmed Clinical Features of Rotavirus Gastroenteritis and Their Association With Different Electropherotypes
title_short Clinical Features of Rotavirus Gastroenteritis and Their Association With Different Electropherotypes
title_sort clinical features of rotavirus gastroenteritis and their association with different electropherotypes
topic Rotavirus, electroforesis, electroferotipos, características clínicas, diarrea, niños
url https://produccioncientificaluz.org/index.php/kasmera/article/view/4700
work_keys_str_mv AT mariazsulbaran clinicalfeaturesofrotavirusgastroenteritisandtheirassociationwithdifferentelectropherotypes
AT antoniojmaldonado clinicalfeaturesofrotavirusgastroenteritisandtheirassociationwithdifferentelectropherotypes
AT yacquelinerojas clinicalfeaturesofrotavirusgastroenteritisandtheirassociationwithdifferentelectropherotypes
AT jesuswbastardo clinicalfeaturesofrotavirusgastroenteritisandtheirassociationwithdifferentelectropherotypes