Agreement of gonioscopy and anterior segment-optical coherence tomography in the assessment of the anterior chamber angle: A cross-sectional study

Purpose: The aim of the study was to evaluate the inter instrument agreement between gonioscopy and anterior segment optical coherence tomography (AS-OCT) in the assessment of the anterior chamber angle (ACA) in eyes with all Van Herick's grades. Methods: A single examiner performed AS-OCT and...

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Main Authors: K Jaseena, P S Rekha
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Kerala Journal of Ophthalmology
Subjects:
Online Access:http://www.kjophthal.com/article.asp?issn=0976-6677;year=2022;volume=34;issue=1;spage=27;epage=31;aulast=Jaseena
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author K Jaseena
P S Rekha
author_facet K Jaseena
P S Rekha
author_sort K Jaseena
collection DOAJ
description Purpose: The aim of the study was to evaluate the inter instrument agreement between gonioscopy and anterior segment optical coherence tomography (AS-OCT) in the assessment of the anterior chamber angle (ACA) in eyes with all Van Herick's grades. Methods: A single examiner performed AS-OCT and gonioscopy with a Goldman single mirror for all study patients. An angle opening distance at 500 μm from the scleral spur in the AS-OCT was considered as the quantitative parameter to assess the ACA. A closed ACA on AS-OCT was defined by the presence of any contact between the iris and angle wall anterior to scleral spur. The agreement between gonioscopy and AS-OCT of the nasal and temporal angles was estimated using the Kappa statistic and the concordance between the instruments using the Lin's concordance coefficient. Results: The mean age of the seventy participants in the study was 52.11 ± 5.37 years. Five (15.15%) of nasal angles and 4 (12.12%) of temporal angles identified as closed by gonioscopy were called as open by AS-OCT. The Kappa statistic (0.59), pairwise correlation (0.60), and Lin's concordance correlation coefficient (0.59) showed only moderate agreement and concordance between AS-OCT and gonioscopy. AS-OCT had a moderate sensitivity (73%) and better specificity (86.4%). Conclusion: The results of our study show that AS-OCT can be used as a clinical diagnostic test but has limited use as a screening test for ACA. The significant proportion of subjects with a mismatch in the categorization of open and closed ACA and the moderate agreement highlights the need for better objective diagnostic criteria for closed ACA.
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spelling doaj.art-de62a3f5321c49f8b759fc97797ab5412022-12-22T02:20:12ZengWolters Kluwer Medknow PublicationsKerala Journal of Ophthalmology0976-66772022-01-01341273110.4103/kjo.kjo_91_21Agreement of gonioscopy and anterior segment-optical coherence tomography in the assessment of the anterior chamber angle: A cross-sectional studyK JaseenaP S RekhaPurpose: The aim of the study was to evaluate the inter instrument agreement between gonioscopy and anterior segment optical coherence tomography (AS-OCT) in the assessment of the anterior chamber angle (ACA) in eyes with all Van Herick's grades. Methods: A single examiner performed AS-OCT and gonioscopy with a Goldman single mirror for all study patients. An angle opening distance at 500 μm from the scleral spur in the AS-OCT was considered as the quantitative parameter to assess the ACA. A closed ACA on AS-OCT was defined by the presence of any contact between the iris and angle wall anterior to scleral spur. The agreement between gonioscopy and AS-OCT of the nasal and temporal angles was estimated using the Kappa statistic and the concordance between the instruments using the Lin's concordance coefficient. Results: The mean age of the seventy participants in the study was 52.11 ± 5.37 years. Five (15.15%) of nasal angles and 4 (12.12%) of temporal angles identified as closed by gonioscopy were called as open by AS-OCT. The Kappa statistic (0.59), pairwise correlation (0.60), and Lin's concordance correlation coefficient (0.59) showed only moderate agreement and concordance between AS-OCT and gonioscopy. AS-OCT had a moderate sensitivity (73%) and better specificity (86.4%). Conclusion: The results of our study show that AS-OCT can be used as a clinical diagnostic test but has limited use as a screening test for ACA. The significant proportion of subjects with a mismatch in the categorization of open and closed ACA and the moderate agreement highlights the need for better objective diagnostic criteria for closed ACA.http://www.kjophthal.com/article.asp?issn=0976-6677;year=2022;volume=34;issue=1;spage=27;epage=31;aulast=Jaseenaagreementanterior chamber anglesconcordanceglaucomagonioscopyoptical coherence tomography
spellingShingle K Jaseena
P S Rekha
Agreement of gonioscopy and anterior segment-optical coherence tomography in the assessment of the anterior chamber angle: A cross-sectional study
Kerala Journal of Ophthalmology
agreement
anterior chamber angles
concordance
glaucoma
gonioscopy
optical coherence tomography
title Agreement of gonioscopy and anterior segment-optical coherence tomography in the assessment of the anterior chamber angle: A cross-sectional study
title_full Agreement of gonioscopy and anterior segment-optical coherence tomography in the assessment of the anterior chamber angle: A cross-sectional study
title_fullStr Agreement of gonioscopy and anterior segment-optical coherence tomography in the assessment of the anterior chamber angle: A cross-sectional study
title_full_unstemmed Agreement of gonioscopy and anterior segment-optical coherence tomography in the assessment of the anterior chamber angle: A cross-sectional study
title_short Agreement of gonioscopy and anterior segment-optical coherence tomography in the assessment of the anterior chamber angle: A cross-sectional study
title_sort agreement of gonioscopy and anterior segment optical coherence tomography in the assessment of the anterior chamber angle a cross sectional study
topic agreement
anterior chamber angles
concordance
glaucoma
gonioscopy
optical coherence tomography
url http://www.kjophthal.com/article.asp?issn=0976-6677;year=2022;volume=34;issue=1;spage=27;epage=31;aulast=Jaseena
work_keys_str_mv AT kjaseena agreementofgonioscopyandanteriorsegmentopticalcoherencetomographyintheassessmentoftheanteriorchamberangleacrosssectionalstudy
AT psrekha agreementofgonioscopyandanteriorsegmentopticalcoherencetomographyintheassessmentoftheanteriorchamberangleacrosssectionalstudy