Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report

Primary hyperaldosteronism is an adrenal abnormality in which there is some degree of autonomy of aldosterone secretion. We report a case of thirty three years old Javanese female presented with uncontrolled hypertension, muscular weakness, cramps  and progressing shortness of breath during working...

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Main Authors: Tjokorda Gde Dalem Pemayun, Ridho Naibaho, Maretina W Wiyati, Ardy Santosa, Siti Amarwati
Format: Article
Language:English
Published: Interna Publishing 2017-11-01
Series:Acta Medica Indonesiana
Subjects:
Online Access:http://actamedindones.org/index.php/ijim/article/view/586
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author Tjokorda Gde Dalem Pemayun
Ridho Naibaho
Maretina W Wiyati
Ardy Santosa
Siti Amarwati
author_facet Tjokorda Gde Dalem Pemayun
Ridho Naibaho
Maretina W Wiyati
Ardy Santosa
Siti Amarwati
author_sort Tjokorda Gde Dalem Pemayun
collection DOAJ
description Primary hyperaldosteronism is an adrenal abnormality in which there is some degree of autonomy of aldosterone secretion. We report a case of thirty three years old Javanese female presented with uncontrolled hypertension, muscular weakness, cramps  and progressing shortness of breath during working for 6 years. She had history of hypertension since age 20. Her serum potassium level was always low that associated with inappropriate kaliuresis. Blood gas analysis revealed metabolic alkalosis. Sonography of the adrenal gland showed right hipoechoic architecture; CT scan of the abdomen confirmed an right adrenal tumor measured 4 cm in its greatest dimension. Endocrine evaluation revealed high plasma aldosterone concentration, suppressed plasma renin activity, aldosterone/renin ratio of 112 and confirmed the diagnosis of primary aldosteronism. She underwent unilateral adrenalectomy. Histopathological report from excised adrenal tumor were compatible to benign adrenocortical adenoma. The patient discharge home with well controlled blood pressure and normokalemia. No clinical symptoms was reported in follow-up.
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spelling doaj.art-de63a65fd37241c78a74689370e48d5c2022-12-22T01:27:00ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322017-11-01493222Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case ReportTjokorda Gde Dalem Pemayun0Ridho Naibaho1Maretina W Wiyati2Ardy Santosa3Siti Amarwati4Department of Internal Medicine Faculty of Medicine, Diponegoro University - Dr. Kariadi Hospital Semarang, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Diponegoro University - Kariadi Hospital, Semarang, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Diponegoro University - Kariadi Hospital, Semarang, IndonesiaDepartment of Surgery, Faculty of Medicine, Diponegoro University - Kariadi Hospital, Semarang, IndonesiaDepartment of Pathology Anatomy, Faculty of Medicine, Diponegoro University - Kariadi Hospital, Semarang, IndonesiaPrimary hyperaldosteronism is an adrenal abnormality in which there is some degree of autonomy of aldosterone secretion. We report a case of thirty three years old Javanese female presented with uncontrolled hypertension, muscular weakness, cramps  and progressing shortness of breath during working for 6 years. She had history of hypertension since age 20. Her serum potassium level was always low that associated with inappropriate kaliuresis. Blood gas analysis revealed metabolic alkalosis. Sonography of the adrenal gland showed right hipoechoic architecture; CT scan of the abdomen confirmed an right adrenal tumor measured 4 cm in its greatest dimension. Endocrine evaluation revealed high plasma aldosterone concentration, suppressed plasma renin activity, aldosterone/renin ratio of 112 and confirmed the diagnosis of primary aldosteronism. She underwent unilateral adrenalectomy. Histopathological report from excised adrenal tumor were compatible to benign adrenocortical adenoma. The patient discharge home with well controlled blood pressure and normokalemia. No clinical symptoms was reported in follow-up.http://actamedindones.org/index.php/ijim/article/view/586hypertensionhypokalemiahyperaldosteronismadrenalectactomyadrenocortical adenoma
spellingShingle Tjokorda Gde Dalem Pemayun
Ridho Naibaho
Maretina W Wiyati
Ardy Santosa
Siti Amarwati
Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report
Acta Medica Indonesiana
hypertension
hypokalemia
hyperaldosteronism
adrenalectactomy
adrenocortical adenoma
title Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report
title_full Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report
title_fullStr Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report
title_full_unstemmed Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report
title_short Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report
title_sort primary hyperaldosteronism due to adrenocortical adenoma a case report
topic hypertension
hypokalemia
hyperaldosteronism
adrenalectactomy
adrenocortical adenoma
url http://actamedindones.org/index.php/ijim/article/view/586
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AT ridhonaibaho primaryhyperaldosteronismduetoadrenocorticaladenomaacasereport
AT maretinawwiyati primaryhyperaldosteronismduetoadrenocorticaladenomaacasereport
AT ardysantosa primaryhyperaldosteronismduetoadrenocorticaladenomaacasereport
AT sitiamarwati primaryhyperaldosteronismduetoadrenocorticaladenomaacasereport