Licochalcone A Suppresses the Proliferation of Osteosarcoma Cells through Autophagy and ATM-Chk2 Activation

Licochalcone A Suppresses the Proliferation of Osteosarcoma Cells through Autophagy and ATM-Chk2 Activation

Licochalcone A, a flavonoid extracted from licorice root, has been shown to exhibit broad anti-inflammatory, anti-bacterial, anticancer, and antioxidative bioactivity. In this study, we investigated the antitumor activity of Licochalcone A against human osteosarcoma cell lines. The data showed that...

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Bibliographic Details
Main Authors: Tai-Shan Shen, Yung-Ken Hsu, Yi-Fu Huang, Hsuan-Ying Chen, Cheng-Pu Hsieh, Chiu-Liang Chen
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Molecules
Subjects:
Licochalcone A
ATM-Chk2
autophagy
osteosarcoma
Online Access:https://www.mdpi.com/1420-3049/24/13/2435

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