Platelet-rich plasma induced healing of a chronic osteochondral defect of the knee
Introduction: Platelet-rich plasma (PRP) has increasingly been used in sports medicine to promote tissue healing. No previous study has demonstrated the effect of PRP alone for treatment of osteochondral defects of the knee. Case presentation: We describe the case of a 37-year-old male who was diagn...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-12-01
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| Series: | Journal of Cartilage & Joint Preservation |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667254523000379 |
| _version_ | 1811153675753619456 |
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| author | Michael R. Baria Ryan Barnes David Flanigan Christopher Kaeding |
| author_facet | Michael R. Baria Ryan Barnes David Flanigan Christopher Kaeding |
| author_sort | Michael R. Baria |
| collection | DOAJ |
| description | Introduction: Platelet-rich plasma (PRP) has increasingly been used in sports medicine to promote tissue healing. No previous study has demonstrated the effect of PRP alone for treatment of osteochondral defects of the knee. Case presentation: We describe the case of a 37-year-old male who was diagnosed with osteochondritis dissecans of the medial femoral condyle in 2000. At that time, he underwent arthroscopic repair. In 2018, he presented for increased medial knee pain and catching. He elected to proceed with an initial PRP injection in 2018 and returned for 3 more injections through 2021. After the 4 injections, magnetic resonance imaging (MRI) demonstrated interval healing of the osteochondral defect with markedly smaller dimensions than the original 2018 MRI [0.7 cm × 0.5 cm]. Conclusion: To our knowledge, this is the first case of MRI-proven healing of an osteochondral defect with PRP (without accompanying cartilage restoration surgery). Ongoing treatment with an anabolic therapy like PRP may facilitate symptom improvement and structural healing. |
| first_indexed | 2024-03-09T01:25:50Z |
| format | Article |
| id | doaj.art-de674d89dbd040a387b8ce4ae83de0cb |
| institution | Directory Open Access Journal |
| issn | 2667-2545 |
| language | English |
| last_indexed | 2024-03-09T01:25:50Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Cartilage & Joint Preservation |
| spelling | doaj.art-de674d89dbd040a387b8ce4ae83de0cb2023-12-10T06:18:55ZengElsevierJournal of Cartilage & Joint Preservation2667-25452023-12-0134100132Platelet-rich plasma induced healing of a chronic osteochondral defect of the kneeMichael R. Baria0Ryan Barnes1David Flanigan2Christopher Kaeding3Department of Physical Medicine and Rehabilitation, The Ohio State University, Columbus, OH, USA; Michael R. Baria, 2835 Fred Taylor Dr, Columbus, OH 43202.Department of Orthopaedics, The Ohio State University, Columbus, OH, USADepartment of Orthopaedics, The Ohio State University, Columbus, OH, USADepartment of Orthopaedics, The Ohio State University, Columbus, OH, USAIntroduction: Platelet-rich plasma (PRP) has increasingly been used in sports medicine to promote tissue healing. No previous study has demonstrated the effect of PRP alone for treatment of osteochondral defects of the knee. Case presentation: We describe the case of a 37-year-old male who was diagnosed with osteochondritis dissecans of the medial femoral condyle in 2000. At that time, he underwent arthroscopic repair. In 2018, he presented for increased medial knee pain and catching. He elected to proceed with an initial PRP injection in 2018 and returned for 3 more injections through 2021. After the 4 injections, magnetic resonance imaging (MRI) demonstrated interval healing of the osteochondral defect with markedly smaller dimensions than the original 2018 MRI [0.7 cm × 0.5 cm]. Conclusion: To our knowledge, this is the first case of MRI-proven healing of an osteochondral defect with PRP (without accompanying cartilage restoration surgery). Ongoing treatment with an anabolic therapy like PRP may facilitate symptom improvement and structural healing.http://www.sciencedirect.com/science/article/pii/S2667254523000379Femoral condyleOsteochondral defectsOsteochondritis dissecansPlatelet-rich plasma |
| spellingShingle | Michael R. Baria Ryan Barnes David Flanigan Christopher Kaeding Platelet-rich plasma induced healing of a chronic osteochondral defect of the knee Journal of Cartilage & Joint Preservation Femoral condyle Osteochondral defects Osteochondritis dissecans Platelet-rich plasma |
| title | Platelet-rich plasma induced healing of a chronic osteochondral defect of the knee |
| title_full | Platelet-rich plasma induced healing of a chronic osteochondral defect of the knee |
| title_fullStr | Platelet-rich plasma induced healing of a chronic osteochondral defect of the knee |
| title_full_unstemmed | Platelet-rich plasma induced healing of a chronic osteochondral defect of the knee |
| title_short | Platelet-rich plasma induced healing of a chronic osteochondral defect of the knee |
| title_sort | platelet rich plasma induced healing of a chronic osteochondral defect of the knee |
| topic | Femoral condyle Osteochondral defects Osteochondritis dissecans Platelet-rich plasma |
| url | http://www.sciencedirect.com/science/article/pii/S2667254523000379 |
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