Chronic rhinosinusitis and emerging treatment options
Patorn Piromchai,1,2 Pornthep Kasemsiri,1,3 Supawan Laohasiriwong,1 Sanguansak Thanaviratananich1 1Department of Otorhinolaryngology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Department of Otolaryngology, Royal Victorian Eye and Ear Hospital/University of Melbourne, East Melb...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2013-06-01
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| Series: | International Journal of General Medicine |
| Online Access: | http://www.dovepress.com/chronic-rhinosinusitis-and-emerging-treatment-options-a13291 |
| _version_ | 1811210115287613440 |
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| author | Piromchai P Kasemsiri P Laohasiriwong S Thanaviratananich S |
| author_facet | Piromchai P Kasemsiri P Laohasiriwong S Thanaviratananich S |
| author_sort | Piromchai P |
| collection | DOAJ |
| description | Patorn Piromchai,1,2 Pornthep Kasemsiri,1,3 Supawan Laohasiriwong,1 Sanguansak Thanaviratananich1 1Department of Otorhinolaryngology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Department of Otolaryngology, Royal Victorian Eye and Ear Hospital/University of Melbourne, East Melbourne, Australia; 3Department of Otolaryngology – Head and Neck Surgery, Wexner Medical Center at the Ohio State University Medical Center, Columbus, Ohio, USA Abstract: This review describes the epidemiology and various treatments in chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Evidence for short-term use of systemic corticosteroids has been shown to be favorable in CRSwNP, but still limited in CRSsNP. Topical corticosteroids improve symptom scores in both CRS subgroups. The role of microbes in CRS is still controversial. Culture-directed antibiotics are recommended for CRSsNP with exacerbation. Long-term use of low dosage antibiotics is recommended for CRSsNP for their anti-inflammatory effects. Other emerging treatment options are also discussed. Keywords: rhinosinusitis, chronic, nasal polyps, therapy, sinus |
| first_indexed | 2024-04-12T04:49:32Z |
| format | Article |
| id | doaj.art-de7390b5666f425ca986b107f7ef2c22 |
| institution | Directory Open Access Journal |
| issn | 1178-7074 |
| language | English |
| last_indexed | 2024-04-12T04:49:32Z |
| publishDate | 2013-06-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of General Medicine |
| spelling | doaj.art-de7390b5666f425ca986b107f7ef2c222022-12-22T03:47:21ZengDove Medical PressInternational Journal of General Medicine1178-70742013-06-012013default453464Chronic rhinosinusitis and emerging treatment optionsPiromchai PKasemsiri PLaohasiriwong SThanaviratananich SPatorn Piromchai,1,2 Pornthep Kasemsiri,1,3 Supawan Laohasiriwong,1 Sanguansak Thanaviratananich1 1Department of Otorhinolaryngology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Department of Otolaryngology, Royal Victorian Eye and Ear Hospital/University of Melbourne, East Melbourne, Australia; 3Department of Otolaryngology – Head and Neck Surgery, Wexner Medical Center at the Ohio State University Medical Center, Columbus, Ohio, USA Abstract: This review describes the epidemiology and various treatments in chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Evidence for short-term use of systemic corticosteroids has been shown to be favorable in CRSwNP, but still limited in CRSsNP. Topical corticosteroids improve symptom scores in both CRS subgroups. The role of microbes in CRS is still controversial. Culture-directed antibiotics are recommended for CRSsNP with exacerbation. Long-term use of low dosage antibiotics is recommended for CRSsNP for their anti-inflammatory effects. Other emerging treatment options are also discussed. Keywords: rhinosinusitis, chronic, nasal polyps, therapy, sinushttp://www.dovepress.com/chronic-rhinosinusitis-and-emerging-treatment-options-a13291 |
| spellingShingle | Piromchai P Kasemsiri P Laohasiriwong S Thanaviratananich S Chronic rhinosinusitis and emerging treatment options International Journal of General Medicine |
| title | Chronic rhinosinusitis and emerging treatment options |
| title_full | Chronic rhinosinusitis and emerging treatment options |
| title_fullStr | Chronic rhinosinusitis and emerging treatment options |
| title_full_unstemmed | Chronic rhinosinusitis and emerging treatment options |
| title_short | Chronic rhinosinusitis and emerging treatment options |
| title_sort | chronic rhinosinusitis and emerging treatment options |
| url | http://www.dovepress.com/chronic-rhinosinusitis-and-emerging-treatment-options-a13291 |
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