β-1,3-Glucan, Which Can Be Targeted by Drugs, Forms a Trabecular Scaffold in the Oocyst Walls of <italic toggle="yes">Toxoplasma</italic> and <italic toggle="yes">Eimeria</italic>

β-1,3-Glucan, Which Can Be Targeted by Drugs, Forms a Trabecular Scaffold in the Oocyst Walls of <italic toggle="yes">Toxoplasma</italic> and <italic toggle="yes">Eimeria</italic>

ABSTRACT The walls of infectious pathogens, which are essential for transmission, pathogenesis, and diagnosis, contain sugar polymers that are defining structural features, e.g., β-1,3-glucan and chitin in fungi, chitin in Entamoeba cysts, β-1,3-GalNAc in Giardia cysts, and peptidoglycans in bacteri...

Full description

Bibliographic Details
Main Authors: G. Guy Bushkin, Edwin Motari, Paula Magnelli, Marc-Jan Gubbels, Jitender P. Dubey, Katarzyna B. Miska, Esther Bullitt, Catherine E. Costello, Phillips W. Robbins, John Samuelson
Format: Article
Language:English
Published: American Society for Microbiology 2012-11-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00258-12

Similar Items

Similar Items