Alterations of Nutritional Status in Children and Adolescents with Acute Lymphoblastic Leukemia
Malnutrition is often observed in pediatric cancer patients and has been recognized as a risk factor for relapse and survival. Maintaining an appropriate nutritional status during anticancer treatment has, therefore, been more and more frequently perceived as an additional requirement for optimal th...
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| Format: | Article |
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MDPI AG
2024-03-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/11/3/334 |
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| author | Izabela Kranjčec Ines Pranjić Jelena Roganović Maja Pavlović Nada Rajačić Sara Sila |
| author_facet | Izabela Kranjčec Ines Pranjić Jelena Roganović Maja Pavlović Nada Rajačić Sara Sila |
| author_sort | Izabela Kranjčec |
| collection | DOAJ |
| description | Malnutrition is often observed in pediatric cancer patients and has been recognized as a risk factor for relapse and survival. Maintaining an appropriate nutritional status during anticancer treatment has, therefore, been more and more frequently perceived as an additional requirement for optimal therapy outcomes. The aim of our study was to establish alterations of nutritional status in 26 children and adolescents treated for acute lymphoblastic leukemia (ALL) at the Children’s Hospital in Zagreb, Croatia, between 2016 and 2021, by using anthropometric measures and serum albumin levels. The majority of patients (53.8% female, median 4 years, 52.2% intermediate-risk leukemia group) had normal weight at the beginning of chemotherapy. The percentage of overweight/obese patients increased from 4.2% at diagnosis to 37.5% at the end of intensive therapy. Apart from a significant increase in body weight (BW) and body mass index (BMI) for age, a notable decline in body height/body length (BH/BL) for age in the observed period was recorded, especially in high-risk leukemia patients. The alterations in serum albumin values were not significant, nor was their correlation with BMI. Dietary consultation was offered to all patients, while children with a decline in BMI and BH/BL received additional nutritional support. |
| first_indexed | 2024-04-24T18:26:09Z |
| format | Article |
| id | doaj.art-de775554053744fbaa33b2d02e4df2bb |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-04-24T18:26:09Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-de775554053744fbaa33b2d02e4df2bb2024-03-27T13:31:09ZengMDPI AGChildren2227-90672024-03-0111333410.3390/children11030334Alterations of Nutritional Status in Children and Adolescents with Acute Lymphoblastic LeukemiaIzabela Kranjčec0Ines Pranjić1Jelena Roganović2Maja Pavlović3Nada Rajačić4Sara Sila5Department of Oncology and Hematology, Children’s Hospital Zagreb, 10000 Zagreb, CroatiaCroatian Academic Centre for Applied Nutritional Science, 10000 Zagreb, CroatiaDepartment of Oncology and Hematology, Children’s Hospital Zagreb, 10000 Zagreb, CroatiaDepartment of Oncology and Hematology, Children’s Hospital Zagreb, 10000 Zagreb, CroatiaDepartment of Oncology and Hematology, Children’s Hospital Zagreb, 10000 Zagreb, CroatiaReferral Center for Pediatric Gastroenterology and Nutrition, Children’s Hospital Zagreb, 10000 Zagreb, CroatiaMalnutrition is often observed in pediatric cancer patients and has been recognized as a risk factor for relapse and survival. Maintaining an appropriate nutritional status during anticancer treatment has, therefore, been more and more frequently perceived as an additional requirement for optimal therapy outcomes. The aim of our study was to establish alterations of nutritional status in 26 children and adolescents treated for acute lymphoblastic leukemia (ALL) at the Children’s Hospital in Zagreb, Croatia, between 2016 and 2021, by using anthropometric measures and serum albumin levels. The majority of patients (53.8% female, median 4 years, 52.2% intermediate-risk leukemia group) had normal weight at the beginning of chemotherapy. The percentage of overweight/obese patients increased from 4.2% at diagnosis to 37.5% at the end of intensive therapy. Apart from a significant increase in body weight (BW) and body mass index (BMI) for age, a notable decline in body height/body length (BH/BL) for age in the observed period was recorded, especially in high-risk leukemia patients. The alterations in serum albumin values were not significant, nor was their correlation with BMI. Dietary consultation was offered to all patients, while children with a decline in BMI and BH/BL received additional nutritional support.https://www.mdpi.com/2227-9067/11/3/334leukemiaacute lymphoblasticchildrennutritional statusanthropometrybody mass index |
| spellingShingle | Izabela Kranjčec Ines Pranjić Jelena Roganović Maja Pavlović Nada Rajačić Sara Sila Alterations of Nutritional Status in Children and Adolescents with Acute Lymphoblastic Leukemia Children leukemia acute lymphoblastic children nutritional status anthropometry body mass index |
| title | Alterations of Nutritional Status in Children and Adolescents with Acute Lymphoblastic Leukemia |
| title_full | Alterations of Nutritional Status in Children and Adolescents with Acute Lymphoblastic Leukemia |
| title_fullStr | Alterations of Nutritional Status in Children and Adolescents with Acute Lymphoblastic Leukemia |
| title_full_unstemmed | Alterations of Nutritional Status in Children and Adolescents with Acute Lymphoblastic Leukemia |
| title_short | Alterations of Nutritional Status in Children and Adolescents with Acute Lymphoblastic Leukemia |
| title_sort | alterations of nutritional status in children and adolescents with acute lymphoblastic leukemia |
| topic | leukemia acute lymphoblastic children nutritional status anthropometry body mass index |
| url | https://www.mdpi.com/2227-9067/11/3/334 |
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