Monoamine transporters: Insights from molecular dynamics simulations
The human monoamine transporters facilitate the reuptake of the neurotransmitters serotonin, dopamine, and norepinephrine from the synaptic cleft. Imbalance in monoaminergic neurotransmission is linked to various diseases including major depression, attention deficit hyperactivity disorder, schizoph...
Main Authors: | Julie eGrouleff, Lucy Kate Ladefoged, Heidi eKoldsø, Birgit eSchiøtt |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-10-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00235/full |
Similar Items
-
Insights to ligand binding to the monoamine transporters – from homology modeling to LeuBAT and dDAT
by: Heidi eKoldsø, et al.
Published: (2015-09-01) -
Designing Modulators of Monoamine Transporters using Virtual Screening Techniques
by: Ole Valente Mortensen, et al.
Published: (2015-09-01) -
Handling of intracellular K+ determines voltage dependence of plasmalemmal monoamine transporter function
by: Shreyas Bhat, et al.
Published: (2021-06-01) -
Vesicular monoamine transporter (VMAT) regional expression and roles in pathological conditions
by: Malik Alwindi, et al.
Published: (2023-11-01) -
Implications for Combination Therapy of Selective Monoamine Reuptake Inhibitors on Dopamine Transporters
by: Hyomin Ahn, et al.
Published: (2023-10-01)