Trends in Prediabetes and Non-Alcoholic Fatty Liver Disease Associated with Abdominal Obesity among Korean Children and Adolescents: Based on the Korea National Health and Nutrition Examination Survey between 2009 and 2018
Investigations on the trends of prediabetes and non-alcoholic fatty liver disease (NAFLD) among children are scarce. We aimed to analyze the trends of prediabetes and NAFLD, as well as their association, among Korean children and adolescents from 2009 to 2018. This study investigated the prevalence...
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MDPI AG
2022-03-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/10/3/584 |
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| author | Kyungchul Song Goeun Park Hye Sun Lee Myeongseob Lee Hae In Lee Jungmin Ahn Eunbyoul Lee Han Saem Choi Junghwan Suh Ahreum Kwon Ho-Seong Kim Hyun Wook Chae |
| author_facet | Kyungchul Song Goeun Park Hye Sun Lee Myeongseob Lee Hae In Lee Jungmin Ahn Eunbyoul Lee Han Saem Choi Junghwan Suh Ahreum Kwon Ho-Seong Kim Hyun Wook Chae |
| author_sort | Kyungchul Song |
| collection | DOAJ |
| description | Investigations on the trends of prediabetes and non-alcoholic fatty liver disease (NAFLD) among children are scarce. We aimed to analyze the trends of prediabetes and NAFLD, as well as their association, among Korean children and adolescents from 2009 to 2018. This study investigated the prevalence of prediabetes, NAFLD, and abdominal obesity among 6327 children and adolescents aged 10–18 years according to age, sex, and body mass index (BMI) using a nationally representative survey. The prevalence of prediabetes, NAFLD, and abdominal obesity increased from 5.14%, 8.17%, and 5.97% respectively, in 2009 to 10.46%, 12.05%, and 10.51% respectively, in 2018. In age-specific analyses, an adverse trend in NAFLD was significant only in participants aged 16–18 years while the prevalence of prediabetes worsened significantly in all age groups. In BMI-specific analyses, the prevalence of prediabetes and NAFLD increased significantly only in participants with normal BMI. In logistic regression analysis, the odds ratio of prediabetes for NAFLD was 1.85 and those of abdominal obesity for prediabetes and NAFLD was 1.85 and 9.34, respectively. Our results demonstrated that the prevalence of prediabetes and NAFLD was increasing in association with abdominal obesity in Korean children and adolescents. |
| first_indexed | 2024-03-09T20:06:17Z |
| format | Article |
| id | doaj.art-de786019e6a94ef09cea00593543d5b8 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-09T20:06:17Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-de786019e6a94ef09cea00593543d5b82023-11-24T00:32:26ZengMDPI AGBiomedicines2227-90592022-03-0110358410.3390/biomedicines10030584Trends in Prediabetes and Non-Alcoholic Fatty Liver Disease Associated with Abdominal Obesity among Korean Children and Adolescents: Based on the Korea National Health and Nutrition Examination Survey between 2009 and 2018Kyungchul Song0Goeun Park1Hye Sun Lee2Myeongseob Lee3Hae In Lee4Jungmin Ahn5Eunbyoul Lee6Han Saem Choi7Junghwan Suh8Ahreum Kwon9Ho-Seong Kim10Hyun Wook Chae11Department of Pediatrics, Severance Children’s Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul 03722, KoreaBiostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul 03722, KoreaBiostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Pediatrics, Severance Children’s Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Pediatrics, Severance Children’s Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Pediatrics, Severance Children’s Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Pediatrics, Severance Children’s Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Pediatrics, Severance Children’s Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Pediatrics, Severance Children’s Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Pediatrics, Severance Children’s Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Pediatrics, Severance Children’s Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul 03722, KoreaDepartment of Pediatrics, Severance Children’s Hospital, Endocrine Research Institute, Yonsei University College of Medicine, Seoul 03722, KoreaInvestigations on the trends of prediabetes and non-alcoholic fatty liver disease (NAFLD) among children are scarce. We aimed to analyze the trends of prediabetes and NAFLD, as well as their association, among Korean children and adolescents from 2009 to 2018. This study investigated the prevalence of prediabetes, NAFLD, and abdominal obesity among 6327 children and adolescents aged 10–18 years according to age, sex, and body mass index (BMI) using a nationally representative survey. The prevalence of prediabetes, NAFLD, and abdominal obesity increased from 5.14%, 8.17%, and 5.97% respectively, in 2009 to 10.46%, 12.05%, and 10.51% respectively, in 2018. In age-specific analyses, an adverse trend in NAFLD was significant only in participants aged 16–18 years while the prevalence of prediabetes worsened significantly in all age groups. In BMI-specific analyses, the prevalence of prediabetes and NAFLD increased significantly only in participants with normal BMI. In logistic regression analysis, the odds ratio of prediabetes for NAFLD was 1.85 and those of abdominal obesity for prediabetes and NAFLD was 1.85 and 9.34, respectively. Our results demonstrated that the prevalence of prediabetes and NAFLD was increasing in association with abdominal obesity in Korean children and adolescents.https://www.mdpi.com/2227-9059/10/3/584prediabetic statenon-alcoholic fatty liver diseasetrendprevalencechildadolescent |
| spellingShingle | Kyungchul Song Goeun Park Hye Sun Lee Myeongseob Lee Hae In Lee Jungmin Ahn Eunbyoul Lee Han Saem Choi Junghwan Suh Ahreum Kwon Ho-Seong Kim Hyun Wook Chae Trends in Prediabetes and Non-Alcoholic Fatty Liver Disease Associated with Abdominal Obesity among Korean Children and Adolescents: Based on the Korea National Health and Nutrition Examination Survey between 2009 and 2018 Biomedicines prediabetic state non-alcoholic fatty liver disease trend prevalence child adolescent |
| title | Trends in Prediabetes and Non-Alcoholic Fatty Liver Disease Associated with Abdominal Obesity among Korean Children and Adolescents: Based on the Korea National Health and Nutrition Examination Survey between 2009 and 2018 |
| title_full | Trends in Prediabetes and Non-Alcoholic Fatty Liver Disease Associated with Abdominal Obesity among Korean Children and Adolescents: Based on the Korea National Health and Nutrition Examination Survey between 2009 and 2018 |
| title_fullStr | Trends in Prediabetes and Non-Alcoholic Fatty Liver Disease Associated with Abdominal Obesity among Korean Children and Adolescents: Based on the Korea National Health and Nutrition Examination Survey between 2009 and 2018 |
| title_full_unstemmed | Trends in Prediabetes and Non-Alcoholic Fatty Liver Disease Associated with Abdominal Obesity among Korean Children and Adolescents: Based on the Korea National Health and Nutrition Examination Survey between 2009 and 2018 |
| title_short | Trends in Prediabetes and Non-Alcoholic Fatty Liver Disease Associated with Abdominal Obesity among Korean Children and Adolescents: Based on the Korea National Health and Nutrition Examination Survey between 2009 and 2018 |
| title_sort | trends in prediabetes and non alcoholic fatty liver disease associated with abdominal obesity among korean children and adolescents based on the korea national health and nutrition examination survey between 2009 and 2018 |
| topic | prediabetic state non-alcoholic fatty liver disease trend prevalence child adolescent |
| url | https://www.mdpi.com/2227-9059/10/3/584 |
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