Nuclear Receptors Resolve Endoplasmic Reticulum Stress to Improve Hepatic Insulin Resistance

Nuclear Receptors Resolve Endoplasmic Reticulum Stress to Improve Hepatic Insulin Resistance

Chronic endoplasmic reticulum (ER) stress culminating in proteotoxicity contributes to the development of insulin resistance and progression to type 2 diabetes mellitus. Pharmacologic interventions targeting several different nuclear receptors have emerged as potential treatments for insulin resista...

Full description

Bibliographic Details
Main Author: Jae Man Lee
Format: Article
Language:English
Published: Korean Diabetes Association 2017-02-01
Series:Diabetes & Metabolism Journal
Subjects:
Diabetes mellitus, type 2
Endoplasmic reticulum stress
Hepatic steatosis
Insulin resistance
Receptors, cytoplasmic and nuclear
Unfolded protein response
Online Access:https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-41-10.pdf

Internet

https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-41-10.pdf

Similar Items