Unipolar Electrogram-Guided versus Lesion Size Index-Guided Catheter Ablation in Patients with Paroxysmal Atrial Fibrillation
Background: This research explores the relationship between the unipolar electrogram (UP-EGM) and lesion size index (LSI) in different regions of continuous circular lesions (CCLs) and to assess the safety and efficacy of UP-EGM-guided versus LSI-guided radiofrequency catheter ablation (RFCA) in pat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Journal of Cardiovascular Development and Disease |
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| Online Access: | https://www.mdpi.com/2308-3425/9/7/229 |
| _version_ | 1797446314955374592 |
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| author | Guohua Fu Bin He Binhao Wang Mingjun Feng Xianfeng Du Jing Liu Yibo Yu Fang Gao Weidong Zhuo Yi Xu Yingbo Qi Huimin Chu |
| author_facet | Guohua Fu Bin He Binhao Wang Mingjun Feng Xianfeng Du Jing Liu Yibo Yu Fang Gao Weidong Zhuo Yi Xu Yingbo Qi Huimin Chu |
| author_sort | Guohua Fu |
| collection | DOAJ |
| description | Background: This research explores the relationship between the unipolar electrogram (UP-EGM) and lesion size index (LSI) in different regions of continuous circular lesions (CCLs) and to assess the safety and efficacy of UP-EGM-guided versus LSI-guided radiofrequency catheter ablation (RFCA) in patients with paroxysmal atrial fibrillation (PAF). Methods: A total of 120 patients with drug-refractory PAF who underwent index RFCA were scheduled to be consecutively included from March 2020 to April 2021. All the patients were randomly divided 1:1 into two groups: the UP-EGM group and the LSI group. The first-pass PVI rate, acute PVI rate, and the sinus rhythm maintenance rate were compared. Results: A total of 120 patients with PAF were included in the study: the UP-EGM group (<i>n</i> = 60) and the LSI group (<i>n</i> = 60). All the LSI values in the UP-EGM group were less than those in the corresponding regions in the LSI group (all <i>p</i> < 0.001). There were no significant differences in the first-pass PVI rate and acute PVI rate between the two groups. After a mean follow-up period of 11.31 ± 1.70 months, the sinus rhythm maintenance rate in the UP-EGM group was comparable to that in the LSI group (90% vs. 91.7%, <i>p</i> = 0.752). Conclusion: UP-EGM-guided and LSI-guided RFCA are both effective and safe in patients with PAF. However, UP-EGM may be more suitable than LSI for guiding individual RFCA. |
| first_indexed | 2024-03-09T13:38:33Z |
| format | Article |
| id | doaj.art-de7dd208e8924858ad4b0da8a185fd20 |
| institution | Directory Open Access Journal |
| issn | 2308-3425 |
| language | English |
| last_indexed | 2024-03-09T13:38:33Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj.art-de7dd208e8924858ad4b0da8a185fd202023-11-30T21:09:24ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252022-07-019722910.3390/jcdd9070229Unipolar Electrogram-Guided versus Lesion Size Index-Guided Catheter Ablation in Patients with Paroxysmal Atrial FibrillationGuohua Fu0Bin He1Binhao Wang2Mingjun Feng3Xianfeng Du4Jing Liu5Yibo Yu6Fang Gao7Weidong Zhuo8Yi Xu9Yingbo Qi10Huimin Chu11Arrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaArrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaArrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaArrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaArrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaArrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaArrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaArrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaArrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaArrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaArrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaArrhythmia Center, Ningbo First Hospital, Ningbo 315000, ChinaBackground: This research explores the relationship between the unipolar electrogram (UP-EGM) and lesion size index (LSI) in different regions of continuous circular lesions (CCLs) and to assess the safety and efficacy of UP-EGM-guided versus LSI-guided radiofrequency catheter ablation (RFCA) in patients with paroxysmal atrial fibrillation (PAF). Methods: A total of 120 patients with drug-refractory PAF who underwent index RFCA were scheduled to be consecutively included from March 2020 to April 2021. All the patients were randomly divided 1:1 into two groups: the UP-EGM group and the LSI group. The first-pass PVI rate, acute PVI rate, and the sinus rhythm maintenance rate were compared. Results: A total of 120 patients with PAF were included in the study: the UP-EGM group (<i>n</i> = 60) and the LSI group (<i>n</i> = 60). All the LSI values in the UP-EGM group were less than those in the corresponding regions in the LSI group (all <i>p</i> < 0.001). There were no significant differences in the first-pass PVI rate and acute PVI rate between the two groups. After a mean follow-up period of 11.31 ± 1.70 months, the sinus rhythm maintenance rate in the UP-EGM group was comparable to that in the LSI group (90% vs. 91.7%, <i>p</i> = 0.752). Conclusion: UP-EGM-guided and LSI-guided RFCA are both effective and safe in patients with PAF. However, UP-EGM may be more suitable than LSI for guiding individual RFCA.https://www.mdpi.com/2308-3425/9/7/229unipolar electrogramlesion indexparoxysmal atrial fibrillationpulmonary vein isolation |
| spellingShingle | Guohua Fu Bin He Binhao Wang Mingjun Feng Xianfeng Du Jing Liu Yibo Yu Fang Gao Weidong Zhuo Yi Xu Yingbo Qi Huimin Chu Unipolar Electrogram-Guided versus Lesion Size Index-Guided Catheter Ablation in Patients with Paroxysmal Atrial Fibrillation Journal of Cardiovascular Development and Disease unipolar electrogram lesion index paroxysmal atrial fibrillation pulmonary vein isolation |
| title | Unipolar Electrogram-Guided versus Lesion Size Index-Guided Catheter Ablation in Patients with Paroxysmal Atrial Fibrillation |
| title_full | Unipolar Electrogram-Guided versus Lesion Size Index-Guided Catheter Ablation in Patients with Paroxysmal Atrial Fibrillation |
| title_fullStr | Unipolar Electrogram-Guided versus Lesion Size Index-Guided Catheter Ablation in Patients with Paroxysmal Atrial Fibrillation |
| title_full_unstemmed | Unipolar Electrogram-Guided versus Lesion Size Index-Guided Catheter Ablation in Patients with Paroxysmal Atrial Fibrillation |
| title_short | Unipolar Electrogram-Guided versus Lesion Size Index-Guided Catheter Ablation in Patients with Paroxysmal Atrial Fibrillation |
| title_sort | unipolar electrogram guided versus lesion size index guided catheter ablation in patients with paroxysmal atrial fibrillation |
| topic | unipolar electrogram lesion index paroxysmal atrial fibrillation pulmonary vein isolation |
| url | https://www.mdpi.com/2308-3425/9/7/229 |
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