Recurrence of Uncomplicated Diverticulitis: A Meta-Analysis
<i>Background and objective:</i> This study aimed to investigate the estimated rate and risk of recurrence of uncomplicated diverticulitis (UCD) after the first episode through a meta-analysis. <i>Methods:</i> Eligible studies were searched and reviewed; 27 studies were inclu...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/6/758 |
| _version_ | 1797484639558828032 |
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| author | Guhyun Kang Soomin Son Young-Min Shin Jung-Soo Pyo |
| author_facet | Guhyun Kang Soomin Son Young-Min Shin Jung-Soo Pyo |
| author_sort | Guhyun Kang |
| collection | DOAJ |
| description | <i>Background and objective:</i> This study aimed to investigate the estimated rate and risk of recurrence of uncomplicated diverticulitis (UCD) after the first episode through a meta-analysis. <i>Methods:</i> Eligible studies were searched and reviewed; 27 studies were included in this study. Subgroup analyses were performed, based on lesion location, medical treatment, follow-up period, and study location. <i>Results:</i> The estimated recurrence rate of UCD was 0.129 (95% confidence interval [CI] 0.102–0.162). The recurrence rates of the right-and left-sided colon were 0.092 (95% CI 27.063–0.133) and 0.153 (95% CI 0.104–0.218), respectively. The recurrence rate according to follow-up period was highest in the subgroup 1–2 years, compared with that of other subgroups. The recurrence rate of the Asian subgroup was significantly lower than that of the non-Asian subgroup (0.092, 95% CI 0.064–0.132 vs. 0.147, 95% CI 0.110–0.192; <i>p</i> = 0.043 in the meta-regression test). There were significant correlations between UCD recurrence and older age and higher body temperature. However, UCD recurrence was not significantly correlated with medications, such as antibiotics or anti-inflammatory drugs. <i>Conclusions:</i> In this study, detailed information on estimated recurrence rates of UCD was obtained. In addition, older age and higher body temperature may be risk factors for UCD recurrence after the first episode. |
| first_indexed | 2024-03-09T23:07:19Z |
| format | Article |
| id | doaj.art-de81aadef7b14a57a8ba57fda228a20f |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T23:07:19Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-de81aadef7b14a57a8ba57fda228a20f2023-11-23T17:52:05ZengMDPI AGMedicina1010-660X1648-91442022-06-0158675810.3390/medicina58060758Recurrence of Uncomplicated Diverticulitis: A Meta-AnalysisGuhyun Kang0Soomin Son1Young-Min Shin2Jung-Soo Pyo3Department of Pathology, Daehang Hospital, Seoul 06699, KoreaDivision of Molecular Life and Chemical Sciences, College of Natural Sciences, Ewha Woman’s University, Seoul 03760, KoreaEulji University School of Medicine, Daejeon 34824, KoreaDepartment of Pathology, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu 11759, Korea<i>Background and objective:</i> This study aimed to investigate the estimated rate and risk of recurrence of uncomplicated diverticulitis (UCD) after the first episode through a meta-analysis. <i>Methods:</i> Eligible studies were searched and reviewed; 27 studies were included in this study. Subgroup analyses were performed, based on lesion location, medical treatment, follow-up period, and study location. <i>Results:</i> The estimated recurrence rate of UCD was 0.129 (95% confidence interval [CI] 0.102–0.162). The recurrence rates of the right-and left-sided colon were 0.092 (95% CI 27.063–0.133) and 0.153 (95% CI 0.104–0.218), respectively. The recurrence rate according to follow-up period was highest in the subgroup 1–2 years, compared with that of other subgroups. The recurrence rate of the Asian subgroup was significantly lower than that of the non-Asian subgroup (0.092, 95% CI 0.064–0.132 vs. 0.147, 95% CI 0.110–0.192; <i>p</i> = 0.043 in the meta-regression test). There were significant correlations between UCD recurrence and older age and higher body temperature. However, UCD recurrence was not significantly correlated with medications, such as antibiotics or anti-inflammatory drugs. <i>Conclusions:</i> In this study, detailed information on estimated recurrence rates of UCD was obtained. In addition, older age and higher body temperature may be risk factors for UCD recurrence after the first episode.https://www.mdpi.com/1648-9144/58/6/758uncomplicated diverticulitisrecurrencemedical treatmentfollow-upmeta-analysis |
| spellingShingle | Guhyun Kang Soomin Son Young-Min Shin Jung-Soo Pyo Recurrence of Uncomplicated Diverticulitis: A Meta-Analysis Medicina uncomplicated diverticulitis recurrence medical treatment follow-up meta-analysis |
| title | Recurrence of Uncomplicated Diverticulitis: A Meta-Analysis |
| title_full | Recurrence of Uncomplicated Diverticulitis: A Meta-Analysis |
| title_fullStr | Recurrence of Uncomplicated Diverticulitis: A Meta-Analysis |
| title_full_unstemmed | Recurrence of Uncomplicated Diverticulitis: A Meta-Analysis |
| title_short | Recurrence of Uncomplicated Diverticulitis: A Meta-Analysis |
| title_sort | recurrence of uncomplicated diverticulitis a meta analysis |
| topic | uncomplicated diverticulitis recurrence medical treatment follow-up meta-analysis |
| url | https://www.mdpi.com/1648-9144/58/6/758 |
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