The neuropeptide PACAP alleviates T. gondii infection-induced neuroinflammation and neuronal impairment

The neuropeptide PACAP alleviates T. gondii infection-induced neuroinflammation and neuronal impairment

Abstract Background Cerebral infection with the protozoan Toxoplasma gondii (T. gondii) is responsible for inflammation of the central nervous system (CNS) contributing to subtle neuronal alterations. Albeit essential for brain parasite control, continuous microglia activation and recruitment of per...

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Bibliographic Details
Main Authors: Caio Andreeta Figueiredo, Henning Peter Düsedau, Johannes Steffen, Stefanie Ehrentraut, Miklos P. Dunay, Gabor Toth, Dora Reglödi, Markus M. Heimesaat, Ildiko Rita Dunay
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Neuroinflammation
Subjects:
PACAP
Neuroinflammation
Toxoplasma gondii
Cerebral toxoplasmosis
Immunomodulation
Neuroprotection
Online Access:https://doi.org/10.1186/s12974-022-02639-z

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