Association between weight-adjusted-waist index and urge urinary incontinence: a cross-sectional study from NHANES 2013 to 2018
Abstract This study aimed to investigate the association between urge urinary incontinence (UUI) and weight-adjusted waist circumference index (WWI), a newly developed measure of obesity. Data from the 2013–2018 National Health and Nutrition Examination Survey (NHANES) were included in the present c...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-01-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-51216-2 |
| _version_ | 1797363473161650176 |
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| author | Haohao Sun Jingxi Huang Hao Tang Bingbing Wei |
| author_facet | Haohao Sun Jingxi Huang Hao Tang Bingbing Wei |
| author_sort | Haohao Sun |
| collection | DOAJ |
| description | Abstract This study aimed to investigate the association between urge urinary incontinence (UUI) and weight-adjusted waist circumference index (WWI), a newly developed measure of obesity. Data from the 2013–2018 National Health and Nutrition Examination Survey (NHANES) were included in the present cross-sectional study. Urge urinary incontinence was identified by self-reported urine leakage before reaching the toilet. Weighted multivariate logistic regression and generalized additive models were used to investigate the connection between WWI and UUI and its nonlinearity. The nonlinear relationship was explored using smoothed curve fitting. Additionally, further analyses were performed on subgroups and interaction tests were conducted. In the study, a total of 14,118 individuals were enrolled, with a UUI prevalence rate of 21.18%. Overall UUI was more prevalent with elevated WWI (OR 1.20, 95% CI 1.13–12.8, P < 0.0001), which similar results were observed in weekly (OR 1.32, 95% CI 1.18–1.48, P < 0.0001) and daily (OR 1.27, 95% CI 1.06–1.53, P = 0.0091) UUI. And this connection remained steady among all subgroups (P > 0.05 for all interactions). Smoothed curve fitting showed no nonlinear relationship between WWI and UUI. In addition, a stronger correlation was found between WWI and UUI risk than other obesity indicators such as waist circumference (WC) and body mass index (BMI). Among US adults, weight-adjusted waist circumference index values are positively associated with elevated odds of UUI and show stronger associations than WC and BMI. Further studies are required to elucidate the causal relationship between WWI and UUI. |
| first_indexed | 2024-03-08T16:20:52Z |
| format | Article |
| id | doaj.art-de884f0c35d14f958a0495f96ccfc2de |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-08T16:20:52Z |
| publishDate | 2024-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-de884f0c35d14f958a0495f96ccfc2de2024-01-07T12:22:31ZengNature PortfolioScientific Reports2045-23222024-01-0114111010.1038/s41598-024-51216-2Association between weight-adjusted-waist index and urge urinary incontinence: a cross-sectional study from NHANES 2013 to 2018Haohao Sun0Jingxi Huang1Hao Tang2Bingbing Wei3Department of Urology, Affiliated Wuxi People’s Hospital of Nanjing Medical UniversityDepartment of Urology, Affiliated Wuxi People’s Hospital of Nanjing Medical UniversityDepartment of Urology, Affiliated Wuxi People’s Hospital of Nanjing Medical UniversityDepartment of Urology, Affiliated Wuxi People’s Hospital of Nanjing Medical UniversityAbstract This study aimed to investigate the association between urge urinary incontinence (UUI) and weight-adjusted waist circumference index (WWI), a newly developed measure of obesity. Data from the 2013–2018 National Health and Nutrition Examination Survey (NHANES) were included in the present cross-sectional study. Urge urinary incontinence was identified by self-reported urine leakage before reaching the toilet. Weighted multivariate logistic regression and generalized additive models were used to investigate the connection between WWI and UUI and its nonlinearity. The nonlinear relationship was explored using smoothed curve fitting. Additionally, further analyses were performed on subgroups and interaction tests were conducted. In the study, a total of 14,118 individuals were enrolled, with a UUI prevalence rate of 21.18%. Overall UUI was more prevalent with elevated WWI (OR 1.20, 95% CI 1.13–12.8, P < 0.0001), which similar results were observed in weekly (OR 1.32, 95% CI 1.18–1.48, P < 0.0001) and daily (OR 1.27, 95% CI 1.06–1.53, P = 0.0091) UUI. And this connection remained steady among all subgroups (P > 0.05 for all interactions). Smoothed curve fitting showed no nonlinear relationship between WWI and UUI. In addition, a stronger correlation was found between WWI and UUI risk than other obesity indicators such as waist circumference (WC) and body mass index (BMI). Among US adults, weight-adjusted waist circumference index values are positively associated with elevated odds of UUI and show stronger associations than WC and BMI. Further studies are required to elucidate the causal relationship between WWI and UUI.https://doi.org/10.1038/s41598-024-51216-2 |
| spellingShingle | Haohao Sun Jingxi Huang Hao Tang Bingbing Wei Association between weight-adjusted-waist index and urge urinary incontinence: a cross-sectional study from NHANES 2013 to 2018 Scientific Reports |
| title | Association between weight-adjusted-waist index and urge urinary incontinence: a cross-sectional study from NHANES 2013 to 2018 |
| title_full | Association between weight-adjusted-waist index and urge urinary incontinence: a cross-sectional study from NHANES 2013 to 2018 |
| title_fullStr | Association between weight-adjusted-waist index and urge urinary incontinence: a cross-sectional study from NHANES 2013 to 2018 |
| title_full_unstemmed | Association between weight-adjusted-waist index and urge urinary incontinence: a cross-sectional study from NHANES 2013 to 2018 |
| title_short | Association between weight-adjusted-waist index and urge urinary incontinence: a cross-sectional study from NHANES 2013 to 2018 |
| title_sort | association between weight adjusted waist index and urge urinary incontinence a cross sectional study from nhanes 2013 to 2018 |
| url | https://doi.org/10.1038/s41598-024-51216-2 |
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