SAPHO syndrome: the clinical case
Syndrome Sapho is a combination of hyperostosis of the sternoclavicular joint with pustulosis of the palms and/or plants, pustular/vulgar psoriasis, or deep acne, which also celebrates spinal cord injury, osteitis and arthritis, including sacroiliitis. As trigger factors, the role of infections, suc...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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Ltd. “The National Academy of Pediatric Science and Innovation”
2017-11-01
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| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/576 |
| _version_ | 1797875272013316096 |
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| author | T. P. Makarova N. N. Firsova H. M. Vakhitov Yu. S. Melnikova L. R. Valieva O. I. Kuzmina |
| author_facet | T. P. Makarova N. N. Firsova H. M. Vakhitov Yu. S. Melnikova L. R. Valieva O. I. Kuzmina |
| author_sort | T. P. Makarova |
| collection | DOAJ |
| description | Syndrome Sapho is a combination of hyperostosis of the sternoclavicular joint with pustulosis of the palms and/or plants, pustular/vulgar psoriasis, or deep acne, which also celebrates spinal cord injury, osteitis and arthritis, including sacroiliitis. As trigger factors, the role of infections, such as Staphylococcus epidermidis, streptococci and viruses, is considered. They are associated with autoimmune post- or parainfectious pathogenesis of the SAPHO syndrome. As with the other seronegative spondyloarthritis important for the pathogenesis of SAPHO syndrome is a factor in hypothermia. Presents a clinical case of the syndrome of Sappho from the group of seronegative spondyloarthritis. Features of the course, the complexity of diagnosis in a particular patient and the possibility of targeted therapy with genetically engineered drugs, are shown. |
| first_indexed | 2024-04-10T01:43:55Z |
| format | Article |
| id | doaj.art-de8cc234a2114dea8cbd42e5d0d6eee5 |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:43:55Z |
| publishDate | 2017-11-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-de8cc234a2114dea8cbd42e5d0d6eee52023-03-13T09:12:44ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282017-11-0162519219710.21508/1027-4065-2017-62-5-192-197517SAPHO syndrome: the clinical caseT. P. Makarova0N. N. Firsova1H. M. Vakhitov2Yu. S. Melnikova3L. R. Valieva4O. I. Kuzmina5ФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РоссииГАУЗ «Детская республиканская клиническая больница» МЗ РТФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РоссииФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РоссииГАУЗ «Детская республиканская клиническая больница» МЗ РТГАУЗ «Детская республиканская клиническая больница» МЗ РТSyndrome Sapho is a combination of hyperostosis of the sternoclavicular joint with pustulosis of the palms and/or plants, pustular/vulgar psoriasis, or deep acne, which also celebrates spinal cord injury, osteitis and arthritis, including sacroiliitis. As trigger factors, the role of infections, such as Staphylococcus epidermidis, streptococci and viruses, is considered. They are associated with autoimmune post- or parainfectious pathogenesis of the SAPHO syndrome. As with the other seronegative spondyloarthritis important for the pathogenesis of SAPHO syndrome is a factor in hypothermia. Presents a clinical case of the syndrome of Sappho from the group of seronegative spondyloarthritis. Features of the course, the complexity of diagnosis in a particular patient and the possibility of targeted therapy with genetically engineered drugs, are shown.https://www.ped-perinatology.ru/jour/article/view/576детисиндром сафопустулезный артроостеитсеронегативные спондилоартритыпсориатический артритостеосклероздиагностикалечение |
| spellingShingle | T. P. Makarova N. N. Firsova H. M. Vakhitov Yu. S. Melnikova L. R. Valieva O. I. Kuzmina SAPHO syndrome: the clinical case Rossijskij Vestnik Perinatologii i Pediatrii дети синдром сафо пустулезный артроостеит серонегативные спондилоартриты псориатический артрит остеосклероз диагностика лечение |
| title | SAPHO syndrome: the clinical case |
| title_full | SAPHO syndrome: the clinical case |
| title_fullStr | SAPHO syndrome: the clinical case |
| title_full_unstemmed | SAPHO syndrome: the clinical case |
| title_short | SAPHO syndrome: the clinical case |
| title_sort | sapho syndrome the clinical case |
| topic | дети синдром сафо пустулезный артроостеит серонегативные спондилоартриты псориатический артрит остеосклероз диагностика лечение |
| url | https://www.ped-perinatology.ru/jour/article/view/576 |
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